Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCDIN3D | Q7Z5W3 | 12/20 | 0.61 |
| ▸ | PDE2A | O00408 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13947363 | 0.84 | PDE2A (0.75) | BCDIN3DPDE2AKDM4ETP53MAPT | |
| SCHEMBL13944374 | 0.80 | PIK3CA (0.58) | BCDIN3DPDE2AKDM4ETP53HTR2C | |
| SCHEMBL13946800 | 0.79 | HTR2C (0.60) | BCDIN3DPDE2AKDM4ETP53HTR2C | |
| SCHEMBL13947036 | 0.79 | PIK3CA (0.60) | BCDIN3DPDE2AKDM4ETP53HTR2C | |
| SCHEMBL13944357 | 0.78 | PIK3CA (0.61) | BCDIN3DPDE2AKDM4ETP53HTR2C | |
| SCHEMBL13943301 | 0.77 | TP53 (0.66) | BCDIN3DPDE2ATP53HTR2CMAPT | |
| SCHEMBL13943736 | 0.77 | BCDIN3D (0.67) | BCDIN3DHTR2C | |
| SCHEMBL13942980 | 0.76 | PDE2A (0.68) | BCDIN3DPDE2AKDM4EMAPTMEN1 | |
| SCHEMBL22806425 | 0.76 | BCDIN3D (1.00) | BCDIN3D | |
| SCHEMBL13943723 | 0.76 | SHMT2 (0.66) | BCDIN3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025678-A1 | Pyrazolo[3,4-d]pyrimidine compounds and their use as modulators of protein kinase | Oncalis AG (CH) | 2009-02-18 | — | — | EP | disclosed |