Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.67 |
| ▸ | BCDIN3D | Q7Z5W3 | 13/20 | 0.65 |
| ▸ | PLK4 | O00444 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13942961 | 0.86 | SHMT2 (0.71) | BCDIN3DTP53SHMT2MEN1KMT2A | |
| SCHEMBL13947566 | 0.86 | PDE2A (0.62) | PDE2ABCDIN3DPLK4TP53SHMT2 | |
| SCHEMBL13947571 | 0.85 | PDE2A (0.67) | PDE2ABCDIN3DPLK4TP53 | |
| SCHEMBL13947561 | 0.84 | PDE2A (0.76) | PDE2ABCDIN3DPLK4TP53 | |
| SCHEMBL13943304 | 0.83 | BCDIN3D (0.78) | BCDIN3DSHMT2 | |
| SCHEMBL13942980 | 0.83 | PDE2A (0.68) | PDE2ABCDIN3DSHMT2MEN1KMT2A | |
| SCHEMBL13947130 | 0.83 | BCDIN3D (0.65) | BCDIN3DTP53SHMT2 | |
| SCHEMBL13947042 | 0.80 | BCDIN3D (0.82) | BCDIN3DSHMT2 | |
| SCHEMBL13943303 | 0.79 | BCDIN3D (0.81) | BCDIN3DSHMT2 | |
| SCHEMBL22805424 | 0.79 | BCDIN3D (1.00) | BCDIN3DSHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025678-A1 | Pyrazolo[3,4-d]pyrimidine compounds and their use as modulators of protein kinase | Oncalis AG (CH) | 2009-02-18 | — | — | EP | disclosed |