Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 14/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | UGCG | Q16739 | 1/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | CALCA | P06881 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13941840 | 0.89 | MC4R (0.40) | MC4RCYP3A4UGCGPROKR1F10 | |
| SCHEMBL13941155 | 0.77 | MC4R (0.39) | MC4RCALCA | |
| SCHEMBL14435581 | 0.76 | UGCG (0.42) | MC4RCYP3A4UGCGPROKR1F10 | |
| SCHEMBL12713076 | 0.73 | CALCA (0.46) | MC4RCYP3A4UGCGF10CALCA | |
| SCHEMBL12713070 | 0.72 | CALCA (0.47) | MC4RCYP3A4UGCGCALCA | |
| SCHEMBL12713085 | 0.71 | CALCA (0.46) | MC4RCYP3A4UGCGF10CALCA | |
| SCHEMBL12738196 | 0.71 | MC4R (0.52) | MC4RCYP3A4UGCGF10CALCA | |
| SCHEMBL12713089 | 0.71 | CALCA (0.45) | MC4RCYP3A4UGCGF10CALCA | |
| SCHEMBL12713110 | 0.70 | CALCA (0.46) | MC4RCYP3A4UGCGF10CALCA | |
| SCHEMBL12713302 | 0.70 | CALCA (0.42) | MC4RCYP3A4UGCGF10CALCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2020405-A1 | Substituted aryl or heteroarylpiperidine derivatives as melanocortin-4 receptor modulators | Santhera Pharmaceuticals (Schweiz) AG (CH) | 2009-02-04 | — | — | EP | disclosed |