Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 4/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | CALCA | P06881 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713076 | 0.90 | CALCA (0.46) | UGCGCYP3A4EPHX2F10MC4R | |
| SCHEMBL14435262 | 0.90 | HRH2 (0.43) | UGCGCYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL12738196 | 0.88 | MC4R (0.52) | UGCGCYP3A4F10MC4RKMT2A | |
| SCHEMBL12713306 | 0.87 | HDAC8 (0.48) | EPHX2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13941840 | 0.87 | MC4R (0.40) | UGCGCYP3A4EPHX2F10MC4R | |
| SCHEMBL12713085 | 0.87 | CALCA (0.46) | UGCGCYP3A4EPHX2F10MC4R | |
| SCHEMBL12713302 | 0.87 | CALCA (0.42) | UGCGCYP3A4EPHX2F10MC4R | |
| SCHEMBL14435958 | 0.87 | CYP1A2 (0.41) | EPHX2F10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13940673 | 0.86 | EPHX2 (0.41) | EPHX2F10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL12713308 | 0.86 | CALCA (0.42) | UGCGCYP3A4EPHX2F10MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096186-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-08-30 | — | — | WO | disclosed |