Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956540 | 0.76 | ENPP2 (0.38) | ALDH1A1ENPP2CYP2A6 | |
| SCHEMBL4195351 | 0.76 | ENPP2 (0.38) | ALDH1A1ENPP2CYP2A6 | |
| SCHEMBL29953730 | 0.74 | MAPT (0.46) | ALDH1A1MAPTCASP1KDM4EGAA | |
| SCHEMBL29952476 | 0.71 | NPSR1 (0.35) | ALDH1A1MAPTHPGDKDM4ECA2 | |
| SCHEMBL5096663 | 0.70 | ROCK1 (0.50) | MAPTKDM4ECYP2A6 | |
| SCHEMBL30785527 | 0.70 | MAPT (0.78) | ALDH1A1SMN1; SMN2MAPTHPGDRAB9A | |
| SCHEMBL30267589 | 0.70 | MAPT (0.78) | ALDH1A1SMN1; SMN2MAPTHPGDRAB9A | |
| SCHEMBL204571 | 0.70 | MAPT (0.78) | ALDH1A1SMN1; SMN2MAPTHPGDRAB9A | |
| SCHEMBL29951054 | 0.69 | CYP17A1 (0.38) | MAPT | |
| SCHEMBL12431299 | 0.69 | PFKFB3 (0.38) | SMN1; SMN2MAPTTSHRTP53CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026345-A1 | THIAZOLIDINONE COMPOUNDS, AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-02-26 | — | — | WO | disclosed |