Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 3/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | SELE | P16581 | 1/20 | 0.30 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.30 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956540 | 1.00 | ENPP2 (0.38) | ENPP2DYRK1AG6PDMIFALDH1A1 | |
| SCHEMBL13730381 | 0.78 | ALDH1A1 (0.39) | DYRK1AG6PDMIFALDH1A1CYP2A6 | |
| SCHEMBL17341212 | 0.76 | CYP2A6 (0.39) | DYRK1AG6PDMIFALDH1A1CYP2A6 | |
| SCHEMBL13951016 | 0.76 | ALDH1A1 (0.44) | ENPP2ALDH1A1CYP2A6 | |
| SCHEMBL2904523 | 0.74 | GPR35 (0.54) | DYRK1AG6PDMIFESR1 | |
| SCHEMBL549183 | 0.73 | G6PD (0.45) | DYRK1AG6PDMIFALDH1A1CYP2A6 | |
| SCHEMBL19135535 | 0.73 | G6PD (0.35) | DYRK1AG6PDMIFALDH1A1CYP2A6 | |
| SCHEMBL17340894 | 0.73 | CSNK1D (0.39) | DYRK1AG6PDMIFALDH1A1CYP2A6 | |
| SCHEMBL23624414 | 0.72 | ENPP2 (0.41) | ENPP2DYRK1AG6PDMIFAPP | |
| SCHEMBL18347531 | 0.71 | ALDH1A1 (0.48) | DYRK1AG6PDMIFALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026345-A1 | THIAZOLIDINONE COMPOUNDS, AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-02-26 | — | — | WO | disclosed |