Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13929244 | 0.93 | PKM (0.46) | PKMTSHRSIGMAR1OPRM1MEN1 | |
| SCHEMBL13929265 | 0.88 | PKM (0.42) | PKMTSHRSIGMAR1OPRM1MEN1 | |
| SCHEMBL13929262 | 0.85 | SIGMAR1 (0.48) | PKMTSHRSIGMAR1OPRM1MEN1 | |
| SCHEMBL13929253 | 0.84 | OGA (0.43) | OGAPKMTSHROPRM1 | |
| SCHEMBL13929251 | 0.81 | TSHR (0.45) | OGAPKMTSHRSIGMAR1MCHR1 | |
| SCHEMBL13929263 | 0.81 | PKM (0.54) | PKMTSHRSIGMAR1OPRM1CCR3 | |
| SCHEMBL13929257 | 0.81 | OGA (0.47) | OGASIGMAR1OPRM1 | |
| SCHEMBL13929239 | 0.79 | PKM (0.52) | PKMTSHRSIGMAR1CCR3 | |
| SCHEMBL13929291 | 0.78 | SIGMAR1 (0.46) | PKMTSHRSIGMAR1OPRM1CCR5 | |
| SCHEMBL13929242 | 0.78 | SIGMAR1 (0.51) | PKMTSHRSIGMAR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054451-A1 | Use of Piperidine Derivatives as Agonists of Chemokine Receptor Activity | EUROSCREEN S.A. (BE) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054451-A1 | Use of Piperidine Derivatives as Agonists of Chemokine Receptor Activity | ACKR3, CCR5, CCR7 | OGA 4575/4885PKM 3209/4885TSHR 636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.