Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GNRHR | P30968 | 10/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13952250 | 0.88 | UTS2R (0.44) | UTS2RTDP1GNRHRRAB9AHTT | |
| SCHEMBL4381260 | 0.87 | UTS2R (0.53) | UTS2RTDP1KDM4EMEN1KMT2A | |
| SCHEMBL13952311 | 0.86 | KDM4E (0.45) | UTS2RTDP1KDM4EMEN1KMT2A | |
| SCHEMBL4374365 | 0.80 | LMNA (0.48) | UTS2RMEN1KMT2AALDH1A1POLB | |
| SCHEMBL4369056 | 0.76 | ALDH1A1 (0.46) | UTS2RKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL4370182 | 0.75 | ALDH1A1 (0.45) | UTS2RKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL4230320 | 0.74 | ALDH1A1 (0.47) | UTS2RTDP1KDM4EMEN1KMT2A | |
| SCHEMBL4228354 | 0.73 | ALDH1A1 (0.52) | UTS2RKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4368938 | 0.73 | CA12 (0.42) | UTS2RTDP1KDM4EMEN1KMT2A | |
| SCHEMBL18668934 | 0.72 | CA12 (0.55) | MEN1KMT2AALDH1A1POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026248-A2 | HYDRAZIDE, AMIDE, PHTHALIMIDE AND PHTHALHYDRAZIDE ANALOGS AS INHIBITORS OF RETROVIRAL INTEGRASE | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH, OFFICE OF TECHNOLOGY TRANSFER (US) | 2009-02-26 | — | — | WO | disclosed |