Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.39 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | GNRHR | P30968 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370182 | 0.88 | ALDH1A1 (0.45) | UTS2RHSP90AA1HSP90B1TRAP1HTT | |
| SCHEMBL13952136 | 0.88 | UTS2R (0.53) | UTS2RHTTTDP1GNRHRRAB9A | |
| SCHEMBL13952311 | 0.77 | KDM4E (0.45) | UTS2RHTTTDP1RXFP1RAB9A | |
| SCHEMBL4369056 | 0.77 | ALDH1A1 (0.46) | UTS2RHSP90AA1HSP90B1TRAP1HTT | |
| SCHEMBL4374365 | 0.75 | LMNA (0.48) | UTS2RHTTRAB9A | |
| SCHEMBL4381260 | 0.75 | UTS2R (0.53) | UTS2RHTTTDP1RAB9A | |
| SCHEMBL4230193 | 0.74 | MEN1 (0.36) | HTTTDP1 | |
| SCHEMBL4368995 | 0.71 | ALDH1A1 (0.43) | RXFP1RAB9A | |
| SCHEMBL4365434 | 0.71 | UTS2R (0.46) | UTS2RTDP1RAB9A | |
| SCHEMBL4368668 | 0.69 | ALDH1A1 (0.48) | UTS2RTDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026248-A2 | HYDRAZIDE, AMIDE, PHTHALIMIDE AND PHTHALHYDRAZIDE ANALOGS AS INHIBITORS OF RETROVIRAL INTEGRASE | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH, OFFICE OF TECHNOLOGY TRANSFER (US) | 2009-02-26 | — | — | WO | disclosed |