Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21730035 | 0.87 | GAA (0.43) | ALDH1A1TSHRALOX15HSD17B10CYP3A4 | |
| SCHEMBL7200380 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15HSD17B10CYP3A4 | |
| SCHEMBL28343864 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15HSD17B10CYP3A4 | |
| SCHEMBL25906960 | 0.80 | CHKA (0.43) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL2869919 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TSHRALOX15HSD17B10CYP3A4 | |
| SCHEMBL24478531 | 0.75 | MAPT (0.45) | ALDH1A1TSHRALOX15HSD17B10CYP3A4 | |
| SCHEMBL19416734 | 0.75 | ALDH1A1 (0.49) | ALDH1A1TSHRALOX15HSD17B10CYP3A4 | |
| SCHEMBL19319170 | 0.75 | SLC2A1 (0.53) | ALDH1A1TSHRALOX15HSD17B10CYP3A4 | |
| SCHEMBL8302666 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRALOX15HSD17B10CYP3A4 | |
| SCHEMBL14274070 | 0.75 | ACHE (0.48) | TDP1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009008906-A2 | THERAPEUTIC COMPOUNDS FOR BLOCKING DNA SYNTHESIS OF POX VIRUSES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-01-15 | — | — | WO | disclosed |