Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.57 |
| ▸ | MST1R | Q04912 | 2/20 | 0.57 |
| ▸ | HGF | P14210 | 1/20 | 0.54 |
| ▸ | AXL | P30530 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13955466 | 1.00 | MET (0.57) | METKDRMST1RHGFAXL | |
| SCHEMBL13955465 | 0.89 | FGFR2 (0.58) | METKDRMST1RAXL | |
| SCHEMBL13787641 | 0.87 | MET (0.59) | METKDRMST1RHGFAXL | |
| SCHEMBL5223147 | 0.87 | MET (0.58) | METKDRMST1RHGFAXL | |
| SCHEMBL21408242 | 0.86 | MET (0.58) | METKDRMST1RHGFAXL | |
| SCHEMBL30216641 | 0.86 | MET (0.58) | METKDRMST1RHGFAXL | |
| SCHEMBL31412927 | 0.86 | AXL (0.61) | METKDRMST1RHGFAXL | |
| SCHEMBL372031 | 0.86 | AXL (0.61) | METKDRMST1RHGFAXL | |
| Ammonia Solution, Strong SCHEMBL2063874 | 0.86 | MET (0.57) | METKDRMST1RHGFAXL | |
| SCHEMBL16933077 | 0.85 | AXL (0.60) | METKDRMST1RHGFAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495104-B2 | Quinoline or quinazoline derivatives inhibiting auto-phosphorylation of fibroblast growth factor receptors | KIRIN BEER KABUSHIKI KAISHA (JP) | 2009-02-24 | — | — | US | disclosed |
| US-20080207617-A1 | Quinoline Derivatives and Quinazoline Derivatives Inhibiting Autophosphrylation of Flt3 and Medicinal Compositions Containing the Same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207617-A1 | Quinoline Derivatives and Quinazoline Derivatives Inhibiting Autophosphrylation of Flt3 and Medicinal Compositions Containing the Same | FLT3, TYRO3, ABL1 | MET 37/4885KDR 148/4885MST1R 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.