Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003559 | 0.83 | TDP1 (0.68) | TDP1CYP1A1MAPK1KDM4EGAA | |
| SCHEMBL15797981 | 0.83 | TDP1 (1.00) | TDP1CYP1A1MAPK1KDM4EGAA | |
| SCHEMBL13957115 | 0.82 | ALDH1A1 (0.56) | TDP1KDM4EGAAL3MBTL1ALDH1A1 | |
| SCHEMBL19427485 | 0.79 | KMT2A (0.51) | TDP1KDM4ECXCR1ALDH1A1HSD17B10 | |
| SCHEMBL9850232 | 0.79 | TDP1 (0.61) | TDP1CYP1A1MAPK1KDM4EGAA | |
| SCHEMBL2748272 | 0.79 | ALDH1A1 (0.53) | TDP1MAPK1KDM4ECXCR1ALDH1A1 | |
| SCHEMBL8756355 | 0.78 | EP300 (0.62) | TDP1KDM4EGAAL3MBTL1ALDH1A1 | |
| SCHEMBL3203835 | 0.77 | APEX1 (0.51) | TDP1CYP1A1KDM4EL3MBTL1CXCR1 | |
| SCHEMBL13166882 | 0.75 | POLB (0.76) | TDP1MAPK1GAAL3MBTL1HPGD | |
| SCHEMBL8072487 | 0.75 | ALDH1A1 (0.50) | TDP1MAPK1KDM4EGAACXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |