Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 3/20 | 0.48 |
| ▸ | PTPN13 | Q12923 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13957114 | 0.82 | TDP1 (0.71) | ALDH1A1POLBHSD17B10TDP1L3MBTL1 | |
| SCHEMBL8756355 | 0.77 | EP300 (0.62) | ALDH1A1POLBMAPTTDP1HTT | |
| SCHEMBL8422543 | 0.76 | ALDH1A1 (0.52) | ALDH1A1POLBMAPTHSD17B10L3MBTL1 | |
| SCHEMBL2748272 | 0.75 | ALDH1A1 (0.53) | ALDH1A1POLBMAPTTDP1HTT | |
| SCHEMBL29087668 | 0.75 | HSD17B10 (0.67) | ALDH1A1POLBMAPTHSD17B10CYP1A2 | |
| SCHEMBL1134320 | 0.74 | HTT (0.59) | ALDH1A1MAPTHSD17B10HTTHPGD | |
| SCHEMBL6596633 | 0.74 | SMN1; SMN2 (0.53) | ALDH1A1POLBMAPTHSD17B10TDP1 | |
| SCHEMBL6012277 | 0.74 | ALDH1A1 (0.51) | ALDH1A1POLBMAPTHSD17B10CYP1A2 | |
| SCHEMBL30587103 | 0.74 | ALDH1A1 (0.51) | ALDH1A1POLBMAPTHSD17B10CYP1A2 | |
| SCHEMBL25556511 | 0.74 | ALDH1A1 (0.51) | ALDH1A1POLBMAPTHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |