Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10133062 | 0.90 | FFAR1 (0.43) | MEN1LMNARAB9AKMT2AIDO1 | |
| SCHEMBL10455047 | 0.78 | ESR1 (0.67) | MMP3BCL2L1FNTAFNTBESR1 | |
| SCHEMBL349504 | 0.74 | ALDH1A1 (0.48) | LMNARAB9ASIGMAR1IDO1 | |
| SCHEMBL61714 | 0.74 | ESR1 (0.50) | FNTAFNTBESR1ESR2MEN1 | |
| SCHEMBL6503361 | 0.74 | CALM1 (0.41) | IDO1 | |
| SCHEMBL717373 | 0.72 | ESR1 (0.78) | FNTAFNTBESR1ESR2KMT2A | |
| SCHEMBL10729584 | 0.71 | TDP1 (0.44) | FNTAFNTBIDO1 | |
| SCHEMBL22250999 | 0.71 | ESR1 (0.54) | ESR1ESR2LMNAKMT2ASIGMAR1 | |
| SCHEMBL28690497 | 0.71 | FNTA (0.47) | FNTAFNTBMEN1LMNAMAPT | |
| SCHEMBL10133086 | 0.71 | HIF1A (0.41) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009009041-A2 | COMPOSITIONS AND METHODS FOR MODULATING A KINASE CASCADE | KINEX PHARMACEUTICALS, LLC (US) | 2009-01-15 | — | — | WO | disclosed |