Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.66 |
| ▸ | APEX1 | P27695 | 1/20 | 0.66 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.66 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.66 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732712 | 0.88 | ALDH1A1 (0.68) | ALDH1A1NPSR1RECQLPOLBTDP1 | |
| SCHEMBL19079736 | 0.81 | PDE4D (0.68) | ALDH1A1NPSR1RECQLPOLBTDP1 | |
| SCHEMBL13856555 | 0.80 | POLB (1.00) | ALDH1A1NPSR1RECQLPOLBTDP1 | |
| SCHEMBL19079693 | 0.79 | PDE4D (0.57) | ALDH1A1NPSR1RECQLPOLBTDP1 | |
| SCHEMBL19079823 | 0.79 | CREBBP (0.78) | ALDH1A1NPSR1RECQLPOLBTDP1 | |
| SCHEMBL19079754 | 0.77 | PDE4D (0.71) | ALDH1A1NPSR1RECQLPOLBTDP1 | |
| SCHEMBL19079750 | 0.75 | ALDH1A1 (0.73) | ALDH1A1NPSR1POLBKDM4EKMT2A | |
| SCHEMBL19079782 | 0.75 | TSHR (0.73) | ALDH1A1NPSR1RECQLPOLBTDP1 | |
| SCHEMBL20228786 | 0.71 | KMT2A (1.00) | ALDH1A1NPSR1RECQLPOLBTDP1 | |
| SCHEMBL19079757 | 0.71 | PDE4D (0.58) | ALDH1A1NPSR1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009010925-A2 | ANNELATED AZAHETEROCYCLIC AMIDES CONTAINING A PYRIMIDINE FRAGMENT AND METHOD FOR THE PRODUCTION AND USE THEREOF | ALLA CHEM, LLC (US) | 2009-01-22 | — | — | WO | disclosed |