Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13963594 | 0.87 | CASP6 (0.64) | ALDH1A1HPGDKDM4EMAPTTRPV1 | |
| SCHEMBL13588247 | 0.84 | TRPV1 (0.50) | ALDH1A1HPGDKDM4EMAPTTRPV1 | |
| SCHEMBL30125341 | 0.83 | TRPV1 (0.64) | KDM4EMAPTTRPV1KMT2ARAB9A | |
| SCHEMBL1805888 | 0.83 | KDM4E (0.57) | ALDH1A1HPGDKDM4EMAPTTRPV1 | |
| SCHEMBL1413170 | 0.83 | TRPV1 (0.64) | KDM4EMAPTTRPV1KMT2ARAB9A | |
| SCHEMBL26885010 | 0.83 | TRPV1 (0.54) | ALDH1A1HPGDKDM4EMAPTTRPV1 | |
| SCHEMBL19417366 | 0.82 | KDM4E (0.55) | ALDH1A1HPGDKDM4EMAPTTRPV1 | |
| SCHEMBL8755640 | 0.81 | PLAU (0.55) | ALDH1A1HPGDKDM4EMAPTTRPV1 | |
| SCHEMBL357522 | 0.80 | KDM4E (0.69) | ALDH1A1HPGDKDM4EMAPTPOLB | |
| SCHEMBL29514721 | 0.80 | KDM4E (0.69) | ALDH1A1HPGDKDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000010-B2 | Alkyl-heterocycle carbamate derivatives, their preparation and their therapeutic application | SANOFI (FR) | 2015-04-07 | — | — | US | disclosed |
| US-9000010-B2 | Alkyl-heterocycle carbamate derivatives, their preparation and their therapeutic application | SANOFI (FR) | 2015-04-07 | — | — | US | disclosed |
| US-20120295909-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2012-11-22 | — | — | US | disclosed |
| US-20120295909-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295909-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | PRMT9, PRMT8, CBR1 | ALDH1A1 1706/4885HPGD 2301/4885KDM4E 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.