Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 9/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368383 | 0.91 | NAMPT (0.46) | NAMPTPOLBCSNK1EKMT2A | |
| SCHEMBL13964269 | 0.87 | NAMPT (0.49) | NAMPTPOLBCSNK1EKDM4E | |
| SCHEMBL14368448 | 0.82 | KDM4E (0.46) | POLBCSNK1EKDM4E | |
| SCHEMBL14368453 | 0.80 | CSNK1E (0.45) | NAMPTCSNK1E | |
| SCHEMBL13964293 | 0.79 | CSNK1E (0.48) | POLBCSNK1EKDM4E | |
| SCHEMBL14368452 | 0.78 | CSNK1E (0.47) | NAMPTCSNK1E | |
| SCHEMBL13964369 | 0.78 | KDM4E (0.49) | POLBCSNK1EKDM4E | |
| SCHEMBL13963964 | 0.78 | CSNK1E (0.49) | NAMPTCSNK1EHPGD | |
| SCHEMBL13964334 | 0.76 | CSNK1E (0.50) | NAMPTCSNK1EKDM4E | |
| SCHEMBL13964196 | 0.76 | CSNK1E (0.52) | CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436291-B1 | INDOLIZINES AS KINASE PROTEIN INHIBITORS | AVENTIS PHARMA SA (FR) | 2009-01-14 | — | — | EP | disclosed |