Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 6/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13368604 | 0.88 | HTR6 (0.62) | HTR6KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL13964855 | 0.84 | HTR6 (0.56) | HTR6KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL13964526 | 0.83 | HTR6 (0.63) | HTR6KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL13964315 | 0.81 | HTR6 (0.64) | HTR6ALDH1A1POLBCYP3A4CYP2C9 | |
| SCHEMBL13368541 | 0.81 | HTR6 (0.60) | HTR6KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL13947148 | 0.80 | HTR6 (0.62) | HTR6KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL13368535 | 0.78 | HTR6 (0.60) | HTR6KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL13368559 | 0.78 | HTR6 (0.74) | HTR6KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL5502315 | 0.78 | HTR6 (1.00) | HTR6KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL14262775 | 0.78 | HTR6 (0.74) | HTR6KMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476746-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2009-01-13 | — | — | US | disclosed |