SCHEMBL1396477

SCHEMBL1396477

CC(C)CC(NC(=O)C(N)Cc1ccccc1)C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.76
MME P08473 2/20 0.71
OPRD1 P41143 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10443978 1.00 LTA4H (0.76) LTA4HMMEOPRD1
SCHEMBL1396480 1.00 LTA4H (0.76) LTA4HMMEOPRD1
SCHEMBL19707913 1.00 LTA4H (0.76) LTA4HMMEOPRD1
SCHEMBL29780321 1.00 LTA4H (0.76) LTA4HMMEOPRD1
Hydrochloric Acid SCHEMBL29262753 0.99 LTA4H (0.74) LTA4HMMEOPRD1
Hydrochloric Acid SCHEMBL30698084 0.99 LTA4H (0.74) LTA4HMMEOPRD1
Hydrochloric Acid SCHEMBL29262752 0.99 LTA4H (0.74) LTA4HMMEOPRD1
SCHEMBL17164618 0.97 LTA4H (0.72) LTA4HMME
SCHEMBL30051506 0.97 LTA4H (0.72) LTA4HMMEOPRD1
SCHEMBL17164621 0.97 LTA4H (0.72) LTA4HMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023083197-A1 METABOLIC MARKER FOR DIAGNOSING OR MONITORING LUNG CANCER, AND SCREENING METHOD THEREFOR AND USE THEREOF 武汉迈特维尔医学科技有限公司 2023-05-19 WO claimed
EP-3805756-A1 SMALL MOLECULE BIOCHEMICAL PROFILING OF INDIVIDUAL SUBJECTS FOR DISEASE DIAGNOSIS AND HEALTH ASSESSMENT Metabolon, Inc. (US) 2021-04-14 EP claimed
CN-106537145-B Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment 麦特博隆股份有限公司 2020-08-25 CN claimed
EP-3129909-A1 SMALL MOLECULE BIOCHEMICAL PROFILING OF INDIVIDUAL SUBJECTS FOR DISEASE DIAGNOSIS AND HEALTH ASSESSMENT Metabolon, Inc. (US) 2017-02-15 EP claimed
WO-2015157407-A1 SMALL MOLECULE BIOCHEMICAL PROFILING OF INDIVIDUAL SUBJECTS FOR DISEASE DIAGNOSIS AND HEALTH ASSESSMENT METABOLON, INC. (US) 2015-10-15 WO claimed
EP-2363116-A1 Sustained-release formulations comprising lofexidine for oral delivery US Worldmeds LLC (US) 2011-09-07 EP claimed
EP-2309993-A1 SKIN PATCHES AND SUSTAINED-RELEASE FORMULATIONS COMPRISING LOFEXIDINE FOR TRANSDERMAL AND ORAL DELIVERY US Worldmeds LLC (US) 2011-04-20 EP claimed
EP-2288334-A1 COMPOSITION AND METHOD FOR TRANSMUCOSAL DELIVERY OF LOFEXIDINE US Worldmeds LLC (US) 2011-03-02 EP claimed
WO-2009158477-A1 SKIN PATCHES AND SUSTAINED-RELEASE FORMULATIONS COMPRISING LOFEXIDINE FOR TRANSDERMAL AND ORAL DELIVERY US WORLDMEDS LLC (US) 2009-12-30 WO claimed
WO-2009120735-A1 COMPOSITION AND METHOD FOR TRANSMUCOSAL DELIVERY OF LOFEXIDINE US WORLDMEDS LLC (US) 2009-10-01 WO claimed
US-7569208-B2 Diagnostic agents for pancreatic exocrine function TOKYO GAS COMPANY LIMITED (JP) 2009-08-04 US claimed
US-20070189966-A1 Diagnostic agents for pancreatic exocrine function TOKYO GAS COMPANY LIMITED 2007-08-16 US claimed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP claimed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US claimed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP claimed
CN-119968127-A Animal food compositions with improved palatability and customizable properties and methods of making the same 玛氏公司 2025-05-09 CN disclosed
CN-118948716-A Application of rice ferment in preparing product with skin care effect 麦吉丽生物科技有限公司 2024-11-15 CN disclosed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP disclosed
EP-0127108-B1 PROCESS FOR PREPARING POLYPEPTIDES MERCK & CO. INC. (US) 1986-12-30 EP disclosed
US-4510083-A POTASSIUM, CESIUM OR RUBIDIUM CARBONATE BUFFER FOR COUPLING OF AMINO ACID N-CARBOXYANHYDRIDE WITH ANOTHER AMINO ACID OR PEPTIDE MERCK & CO., INC. (US) 1985-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070189966-A1 Diagnostic agents for pancreatic exocrine function AMY2A, IAPP, AMY1A LTA4H 2053/4885MME 441/4885OPRD1 2653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.