Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13964802 | 0.85 | CHRM1 (0.59) | CHRM1SMN1; SMN2GAATDP1MEN1 | |
| SCHEMBL12482578 | 0.81 | CHRM1 (0.59) | CHRM1SMN1; SMN2GAATDP1MEN1 | |
| Hydrochloric Acid SCHEMBL1999076 | 0.79 | CHRM1 (0.57) | CHRM1SMN1; SMN2GAATDP1MEN1 | |
| SCHEMBL26095936 | 0.79 | ALDH1A1 (0.56) | CHRM1SMN1; SMN2GAATDP1MEN1 | |
| SCHEMBL11039671 | 0.79 | SMN1; SMN2 (0.59) | CHRM1SMN1; SMN2GAATDP1MEN1 | |
| SCHEMBL274448 | 0.79 | SMN1; SMN2 (0.59) | CHRM1SMN1; SMN2GAATDP1MEN1 | |
| SCHEMBL1437816 | 0.78 | CHRM1 (0.56) | CHRM1SMN1; SMN2GAATDP1MEN1 | |
| Hydrochloric Acid SCHEMBL4788803 | 0.77 | SMN1; SMN2 (0.57) | CHRM1SMN1; SMN2GAATDP1MEN1 | |
| Hydrochloric Acid SCHEMBL14311961 | 0.77 | SMN1; SMN2 (0.57) | CHRM1SMN1; SMN2GAATDP1MEN1 | |
| SCHEMBL29584230 | 0.77 | CHRM1 (0.55) | CHRM1SMN1; SMN2GAATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335369-A | GEM-disubstituted piperidine melanocortin subtype-2 receptor (MC 2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2022-11-11 | — | — | CN | disclosed |