Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | THPO | P40225 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 2/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28760507 | 0.82 | HSD17B10 (0.74) | HSD17B10KDM4EMAPTHPGDTDP1 | |
| SCHEMBL28760511 | 0.82 | HSD17B10 (0.74) | HSD17B10KDM4EMAPTHPGDTDP1 | |
| SCHEMBL29658794 | 0.82 | HSD17B10 (0.74) | HSD17B10KDM4EMAPTHPGDTDP1 | |
| SCHEMBL10728310 | 0.82 | HSD17B10 (0.69) | HSD17B10KDM4EMAPTHPGDTDP1 | |
| SCHEMBL12608355 | 0.82 | HSD17B10 (0.48) | HSD17B10KDM4EMAPTHPGDTDP1 | |
| SCHEMBL1396585 | 0.81 | ALDH1A1 (0.64) | HSD17B10KDM4EMAPTHPGDTDP1 | |
| SCHEMBL13987942 | 0.80 | HSD17B10 (0.75) | HSD17B10KDM4EMAPTHPGDTDP1 | |
| SCHEMBL11654746 | 0.80 | HSD17B10 (0.70) | HSD17B10KDM4EMAPTHPGDTDP1 | |
| SCHEMBL11656038 | 0.80 | MAPT (0.66) | HSD17B10KDM4EMAPTHPGDTDP1 | |
| SCHEMBL10530662 | 0.80 | POLB (0.66) | HSD17B10KDM4EMAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288632-B1 | MULTIFUNCTIONAL COATINGS | Université de Liège (BE) | 2017-04-05 | — | — | EP | disclosed |
| US-8404760-B2 | Filled dental material based on polymerizable dihydroxy-phenylalanine derivatives | IVOCLAR VIVADENT AG (LI) | 2013-03-26 | — | — | US | disclosed |
| US-8404760-B2 | Filled dental material based on polymerizable dihydroxy-phenylalanine derivatives | IVOCLAR VIVADENT AG (LI) | 2013-03-26 | — | — | US | disclosed |
| EP-2324810-A1 | Filled dental material based on polymerisable dihydroxyphenylalanine derivatives | Ivoclar Vivadent AG (LI) | 2011-05-25 | — | — | EP | disclosed |
| US-20110118380-A1 | Filled Dental Material Based on Polymerizable Dihydroxy-Phenylalanine Derivatives | IVOCLAR VIVADENT AG (LI) | 2011-05-19 | — | — | US | disclosed |
| US-20110118380-A1 | Filled Dental Material Based on Polymerizable Dihydroxy-Phenylalanine Derivatives | IVOCLAR VIVADENT AG (LI) | 2011-05-19 | — | — | US | disclosed |
| US-20110076504-A1 | MULTIFUNCTIONAL COATINGS | UNIVERSITE DE LIEGE (BE) | 2011-03-31 | — | — | US | disclosed |
| EP-2288632-A2 | MULTIFUNCTIONAL COATINGS | Université de Liège (BE) | 2011-03-02 | — | — | EP | disclosed |
| WO-2009147007-A2 | MULTIFUNCTIONAL COATINGS | UNIVERSITE DE LIEGE (BE) | 2009-12-10 | — | — | WO | disclosed |
| EP-2130844-A1 | Multifunctional coatings | Université de Liège (BE) | 2009-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118380-A1 | Filled Dental Material Based on Polymerizable Dihydroxy-Phenylalanine Derivatives | PAH, FANCI, P4HA1 | HSD17B10 439/4885KDM4E 1100/4885MAPT 879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.