Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13965822 | 0.87 | KDM4E (0.39) | KDM4EUSP2HPGDHSD17B10NPSR1 | |
| SCHEMBL13965819 | 0.86 | PDE7A (0.35) | KDM4EUSP2HPGDHSD17B10NPSR1 | |
| SCHEMBL13965817 | 0.85 | KDM4E (0.34) | KDM4EUSP2HPGDHSD17B10NPSR1 | |
| SCHEMBL1048676 | 0.84 | MEN1 (0.52) | KCNH2KDM4EUSP2HPGDHSD17B10 | |
| SCHEMBL13965827 | 0.81 | KDM4E (0.39) | KDM4EUSP2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL13965821 | 0.80 | OPRM1 (0.32) | KDM4EUSP2IDO1MEN1MAPT | |
| SCHEMBL13965820 | 0.80 | HTR2A (0.40) | KDM4EHSD17B10NPSR1ALDH1A1IDO1 | |
| SCHEMBL12958629 | 0.79 | KDM4E (0.46) | KDM4EUSP2HPGDHSD17B10NPSR1 | |
| SCHEMBL1052311 | 0.76 | MEN1 (0.61) | KDM4EUSP2HPGDHSD17B10NPSR1 | |
| SCHEMBL1051294 | 0.74 | MEN1 (0.54) | KCNH2KDM4EUSP2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295903-A1 | FLAVIN DERIVATIVES | BLOUNT KENNETH F (US) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295903-A1 | FLAVIN DERIVATIVES | BLVRB, FLAD1, FDPS | KCNH2 2989/4885KDM4E 1942/4885USP2 3808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.