Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 14/20 | 0.44 |
| ▸ | ESR1 | P03372 | 12/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29089151 | 0.76 | MEN1 (0.49) | ESR2ESR1MEN1KMT2A | |
| SCHEMBL11850583 | 0.70 | TP53 (0.42) | L3MBTL1MEN1KMT2A | |
| SCHEMBL25097790 | 0.68 | CA3 (0.53) | ESR2ESR1MEN1KMT2AKDM4E | |
| SCHEMBL7892479 | 0.68 | TP53 (0.46) | L3MBTL1MEN1KMT2A | |
| SCHEMBL15580875 | 0.66 | SMN1; SMN2 (0.58) | MEN1KMT2A | |
| SCHEMBL11865942 | 0.66 | ESR2 (0.52) | ESR2ESR1MEN1KMT2A | |
| SCHEMBL16689762 | 0.66 | SMN1; SMN2 (0.58) | MEN1KMT2A | |
| SCHEMBL10678658 | 0.65 | SLC6A3 (0.52) | ESR2ESR1MEN1KMT2AKDM4E | |
| SCHEMBL10678669 | 0.65 | SLC6A3 (0.52) | ESR2ESR1MEN1KMT2AKDM4E | |
| SCHEMBL10678651 | 0.65 | SLC6A3 (0.52) | ESR2ESR1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009012954-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2009-01-29 | — | — | WO | disclosed |