Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13786667 | 0.92 | ALDH1A1 (0.48) | GAAALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL14204715 | 0.89 | DHODH (0.43) | GAAALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL14221634 | 0.88 | MAOB (0.46) | GAAALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL14206850 | 0.86 | GAA (0.52) | GAAALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL14035606 | 0.85 | GAA (0.46) | GAAALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL13786603 | 0.85 | MAOB (0.53) | GAAALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL14205774 | 0.84 | ERN1 (0.47) | GAAALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL13971251 | 0.81 | ALDH1A1 (0.47) | GAAALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL13786439 | 0.80 | MAOB (0.46) | GAAALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL10533050 | 0.79 | GAA (0.54) | GAAALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039829-A2 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-04-03 | — | — | WO | disclosed |