Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNPH1 | O43598 | 4/20 | 1.00 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.86 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.86 |
| ▸ | NT5E | P21589 | 5/20 | 0.84 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.73 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.67 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.67 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14700471 | 1.00 | DNPH1 (1.00) | DNPH1P2RX3P2RX2NT5EADORA3 | |
| SCHEMBL13957724 | 1.00 | DNPH1 (1.00) | DNPH1P2RX3P2RX2NT5EADORA3 | |
| SCHEMBL17022278 | 1.00 | DNPH1 (1.00) | DNPH1P2RX3P2RX2NT5EADORA3 | |
| SCHEMBL29564113 | 1.00 | DNPH1 (1.00) | DNPH1P2RX3P2RX2NT5EADORA3 | |
| SCHEMBL218999 | 1.00 | DNPH1 (1.00) | DNPH1P2RX3P2RX2NT5EADORA3 | |
| SCHEMBL23440101 | 1.00 | DNPH1 (1.00) | DNPH1P2RX3P2RX2NT5EADORA3 | |
| SCHEMBL9607782 | 0.93 | P2RX3 (0.98) | DNPH1P2RX3P2RX2NT5EADORA3 | |
| SCHEMBL30076630 | 0.93 | P2RX3 (0.98) | DNPH1P2RX3P2RX2NT5EADORA3 | |
| SCHEMBL29941330 | 0.93 | P2RX3 (0.98) | DNPH1P2RX3P2RX2NT5EADORA3 | |
| SCHEMBL13033867 | 0.93 | P2RX3 (0.98) | DNPH1P2RX3P2RX2NT5EADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029949-A1 | GPCR Ligands Identified by Computational Modeling | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029949-A1 | GPCR Ligands Identified by Computational Modeling | LPAR3, LPAR2, LPAR1 | DNPH1 4103/4885P2RX3 763/4885P2RX2 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.