Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.98 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.98 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.87 |
| ▸ | NT5E | P21589 | 5/20 | 0.80 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.78 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.75 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.75 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.75 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941330 | 1.00 | P2RX3 (0.98) | P2RX3P2RX2DNPH1NT5EP2RX4 | |
| SCHEMBL30076630 | 1.00 | P2RX3 (0.98) | P2RX3P2RX2DNPH1NT5EP2RX4 | |
| SCHEMBL13033867 | 1.00 | P2RX3 (0.98) | P2RX3P2RX2DNPH1NT5EP2RX4 | |
| SCHEMBL4319955 | 1.00 | P2RX3 (0.98) | P2RX3P2RX2DNPH1NT5EP2RX4 | |
| SCHEMBL14178287 | 0.99 | P2RX3 (1.00) | P2RX3P2RX2DNPH1NT5EP2RX4 | |
| SCHEMBL15794372 | 0.99 | P2RX3 (1.00) | P2RX3P2RX2DNPH1NT5EP2RX4 | |
| SCHEMBL30012699 | 0.99 | P2RX3 (1.00) | P2RX3P2RX2DNPH1NT5EP2RX4 | |
| SCHEMBL23440101 | 0.93 | DNPH1 (1.00) | P2RX3P2RX2DNPH1NT5EP2RX4 | |
| SCHEMBL14700471 | 0.93 | DNPH1 (1.00) | P2RX3P2RX2DNPH1NT5EP2RX4 | |
| SCHEMBL17022278 | 0.93 | DNPH1 (1.00) | P2RX3P2RX2DNPH1NT5EP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135092-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2012-05-31 | — | — | US | disclosed |
| US-20100292135-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292135-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | RECQL, DNA2, WRN | P2RX3 1480/4885P2RX2 1581/4885DNPH1 2249/4885 |
| US-20120135092-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | RECQL, WRN, ADAR | P2RX3 757/4885P2RX2 763/4885DNPH1 2013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.