Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424361 | 0.81 | HDAC1 (0.37) | ALDH1A1KDM4EMEN1KMT2AHIF1A | |
| SCHEMBL13959081 | 0.78 | HDAC1 (0.49) | ALDH1A1KDM4EMEN1KMT2AHDAC1 | |
| SCHEMBL13959082 | 0.78 | HDAC1 (0.49) | MEN1KMT2AHDAC1HDAC2CYP1A2 | |
| SCHEMBL13959104 | 0.77 | TERT (0.47) | — | |
| SCHEMBL13959073 | 0.75 | NCF1 (0.50) | ALDH1A1KDM4EHDAC1HDAC2CYP1A2 | |
| SCHEMBL8233885 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KDM4ECYP1A2CYP3A4MAPT | |
| SCHEMBL13958894 | 0.73 | CYSLTR1 (0.49) | KDM4EHDAC1HDAC2HPGDHSD17B10 | |
| SCHEMBL13959075 | 0.70 | PDE10A (0.42) | MEN1KMT2AHDAC1HDAC2CYP1A2 | |
| SCHEMBL13973340 | 0.69 | PARP1 (0.35) | ALDH1A1KDM4EHDAC1HDAC2HPGD | |
| SCHEMBL18710339 | 0.67 | MAPT (0.44) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090011977-A1 | Novel Lipopeptides as Antibacterial Agents | HILL JASON | 2009-01-08 | — | — | US | disclosed |
| US-20080287347-A1 | Novel Lipopeptides as Antibacterial Agents | CUBIST PHARMACEUTICALS, INC. | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287347-A1 | Novel Lipopeptides as Antibacterial Agents | CLPTM1, NGLY1, VIP | ALDH1A1 4742/4885KDM4E 4432/4885MEN1 3618/4885 |
| US-20090011977-A1 | Novel Lipopeptides as Antibacterial Agents | CLPTM1, NGLY1, VIP | ALDH1A1 4742/4885KDM4E 4432/4885MEN1 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.