Sugi Predict

Sugi Predict / Compounds / SCHEMBL1397309

SCHEMBL1397309

SCHEMBL1397309

NC(=S)Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 3/20 0.53
▸ KMT2A Q03164 3/20 0.53
▸ ALDH1A1 P00352 2/20 0.53
▸ LMNA P02545 1/20 0.53
▸ HTT P42858 1/20 0.53
▸ SMN1; SMN2 Q16637 1/20 0.53
▸ CES2 O00748 1/20 0.50
▸ CES1 P23141 1/20 0.50
▸ AKR1B1 P15121 1/20 0.50
▸ PKM P14618 1/20 0.50
▸ CTSL P07711 1/20 0.50
▸ HIF1A Q16665 1/20 0.45
▸ ALOX12 P18054 2/20 0.44
▸ HPGD P15428 1/20 0.44
▸ LOXL2 Q9Y4K0 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ HDAC8 Q9BY41 1/20 0.43
▸ HDAC6 Q9UBN7 1/20 0.43
▸ POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8706873 0.81 CYP1A2 (0.59) GAAKMT2ALMNASMN1; SMN2HIF1A
SCHEMBL27654573 0.78 PKM (0.55) GAAKMT2AALDH1A1LMNAHTT
SCHEMBL5184996 0.78 CES1 (0.55) GAAKMT2AALDH1A1LMNAHTT
SCHEMBL8993215 0.78 CES1 (0.55) GAAKMT2AALDH1A1LMNAHTT
SCHEMBL28085046 0.78 CES1 (0.55) GAAKMT2AALDH1A1LMNAHTT
SCHEMBL1096270 0.78 CES1 (0.55) GAAKMT2AALDH1A1LMNAHTT
SCHEMBL8135240 0.77 CA2 (0.60) KMT2AALDH1A1LMNAIDO1
SCHEMBL9293412 0.77 MAOB (0.47) ALDH1A1HTTSMN1; SMN2HPGDTSHR
SCHEMBL3268826 0.77 CES1 (0.54) GAAKMT2AALDH1A1LMNAHTT
SCHEMBL3368202 0.76 CES1 (0.52) GAAKMT2AALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118028838-A Electrochemical in-situ preparation method and application of sulfur-doped copper nanoparticles 中汽研汽车检验中心（天津）有限公司 2024-05-14 — — CN claimed
EP-1126833-A4 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES INC (US) 2004-09-08 — — EP claimed
EP-1126833-A2 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2001-08-29 — — EP claimed
EP-0682663-B1 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS UPJOHN CO (US) 2001-04-18 — — EP claimed
WO-2000025768-A1 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2000-05-11 — — WO claimed
US-5686486-A 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl b!pyran-2-ones useful to treat retroviral infections PHARMACIA & UPJOHN COMPANY (US) 1997-11-11 — — US claimed
EP-0754184-A1 CEPHALOSPORIN ANTIBIOTICS Microcide Pharmaceuticals, Inc. (US) 1997-01-22 — — EP claimed
WO-1995026966-A1 CEPHALOSPORIN ANTIBIOTICS MICROCIDE PHARMACEUTICALS, INC. (US) 1995-10-12 — — WO claimed
US-4407815-A AMINO ACID DERIVATIVE ANTIBIOTICS BEECHAM GROUP LIMITED (GB) 1983-10-04 — — US claimed
US-4342869-A Cephalosporin antibiotics MERCK & CO., INC. (US) 1982-08-03 — — US claimed
US-4338437-A Cephalosporin antibiotics MERCK & CO., INC. (US) 1982-07-06 — — US claimed
US-4338438-A Cephalosporin antibiotics MERCK & CO., INC. (US) 1982-07-06 — — US claimed
US-4297488-A 7-α-Methoxy cephalosporins MERCK & CO., INC. (US) 1981-10-27 — — US claimed
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS SERVIER LAB (FR) 2026-01-01 — — US disclosed
US-20250296953-A1 3,4-THIAZOLO-STEROIDS AND METHODS OF MAKING AND USING THE SAME Arkansas State University - Jonesboro 2025-09-25 — — US disclosed
US-12319713-B2 3,4-thiazolo-steroids and methods of making and using the same Arkansas State University—Jonesboro (US) 2025-06-03 — — US disclosed
US-4038275-A PROCESS FOR PREPARATION OF 3-HYDROXYMETHYLCEPHEMS ELI LILLY AND COMPANY (US) 1977-07-26 — — US disclosed
US-3980655-A Basically substituted 1,4-dihydro-2H-isoquinoline derivatives and process for preparing them HOECHST AKTIENGESELLSCHAFT (DT) 1976-09-14 — — US disclosed
US-3954732-A BACTERICIDAL PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-05-04 — — US disclosed
US-3907784-A 7-Halophenylthioacetamido cephalosporins LILLY CO ELI 1975-09-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12319713-B2 3,4-thiazolo-steroids and methods of making and using the same HSD17B7, HSD17B3, NR3C2 GAA 3129/4885KMT2A 4424/4885ALDH1A1 826/4885
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS BCL2, BCL2A1, BAX GAA 1860/4885KMT2A 4742/4885ALDH1A1 1848/4885
US-20250296953-A1 3,4-THIAZOLO-STEROIDS AND METHODS OF MAKING AND USING THE SAME HSD17B7, HSD17B3, NR3C2 GAA 3129/4885KMT2A 4424/4885ALDH1A1 826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.