Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | SNCA | P37840 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109009 | 0.85 | TOP1 (0.89) | TOP1ALOX15SNCAKMT2APKM | |
| SCHEMBL29429233 | 0.85 | TOP1 (0.89) | TOP1ALOX15SNCAKMT2APKM | |
| SCHEMBL17013406 | 0.83 | NPC1 (0.69) | ALOX15KMT2APKMNPC1RAB9A | |
| SCHEMBL8420420 | 0.83 | NPC1 (0.69) | ALOX15KMT2APKMNPC1RAB9A | |
| SCHEMBL11793228 | 0.82 | KMT2A (0.73) | TOP1ALOX15KMT2APKMNPC1 | |
| SCHEMBL12937374 | 0.78 | TOP1 (0.74) | TOP1ALOX15SNCAKMT2ANPC1 | |
| SCHEMBL8348359 | 0.78 | AURKB (0.64) | TOP1ALOX15KMT2APKMNPC1 | |
| Protocatechuic Acid SCHEMBL4531319 | 0.77 | CA12 (0.68) | TOP1TERT | |
| SCHEMBL12706788 | 0.77 | TOP1 (0.72) | TOP1ALOX15SNCAKMT2ANPC1 | |
| SCHEMBL84733 | 0.77 | ARG1 (0.48) | TOP1ALOX15SNCAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |