SCHEMBL13974155

SCHEMBL13974155

CCOc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2/C(N)=N/O)cc1

nearest known ligand 0.82

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 2/20 0.66
ABCB11 O95342 1/20 0.66
EGFR P00533 1/20 0.66
ERBB2 P04626 1/20 0.66
CYP3A4 P08684 1/20 0.66
ADORA3 P0DMS8 1/20 0.66
CYP2C9 P11712 1/20 0.66
ADRB3 P13945 1/20 0.66
ADRA2B P18089 1/20 0.66
SLC6A2 P23975 1/20 0.66
TBXAS1 P24557 1/20 0.66
HTR2C P28335 1/20 0.66
PPARG P37231 1/20 0.66
HTR2B P41595 1/20 0.66
AGTR2 P50052 1/20 0.66
PDE3A Q14432 1/20 0.66
LTB4R2 Q9NPC1 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15550328 1.00 AGTR1 (0.66) AGTR1ABCB11EGFRERBB2CYP3A4
SCHEMBL15551208 1.00 AGTR1 (0.66) AGTR1ABCB11EGFRERBB2CYP3A4
SCHEMBL13745398 0.92 AGTR1 (0.65) AGTR1ABCB11EGFRERBB2CYP3A4
SCHEMBL16367902 0.91 AGTR2 (0.55) AGTR1ABCB11EGFRERBB2CYP3A4
SCHEMBL15157485 0.91 AGTR2 (0.55) AGTR1ABCB11EGFRERBB2CYP3A4
SCHEMBL17695745 0.91 AGTR2 (0.55) AGTR1ABCB11EGFRERBB2CYP3A4
SCHEMBL15157487 0.91 AGTR2 (0.55) AGTR1ABCB11EGFRERBB2CYP3A4
SCHEMBL31364599 0.91 PPARG (0.70) AGTR1ABCB11EGFRERBB2CYP3A4
SCHEMBL29257718 0.91 PPARG (0.70) AGTR1ABCB11EGFRERBB2CYP3A4
SCHEMBL3975959 0.91 AGTR1 (0.75) AGTR1ABCB11EGFRERBB2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012157980-A2 MANUFACTURING METHOD OF AZILSARTAN HANMI FINE CHEMICAL CO., LTD. (KR) 2012-11-22 WO disclosed