Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | EGFR | P00533 | 1/20 | 0.66 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.66 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.66 |
| ▸ | PPARG | P37231 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.66 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.66 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13974155 | 1.00 | AGTR1 (0.66) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL15551208 | 1.00 | AGTR1 (0.66) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL13745398 | 0.92 | AGTR1 (0.65) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL16367902 | 0.91 | AGTR2 (0.55) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL15157485 | 0.91 | AGTR2 (0.55) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL17695745 | 0.91 | AGTR2 (0.55) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL15157487 | 0.91 | AGTR2 (0.55) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL31364599 | 0.91 | PPARG (0.70) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL29257718 | 0.91 | PPARG (0.70) | AGTR1ABCB11EGFRERBB2CYP3A4 | |
| SCHEMBL3975959 | 0.91 | AGTR1 (0.75) | AGTR1ABCB11EGFRERBB2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9527850-B2 | Benzyl piperidine compounds as lysophosphatidic acid (LPA) receptor antagonist | MERCK PATENT GMBH (DE) | 2016-12-27 | — | — | US | claimed |
| WO-2013186792-A2 | PROCESS FOR THE PREPARATION OF (5-METHYL-2-OXO-L,3-DIOXOI-4-VL)METHVL 2- ETHOXV-L-{[2'-(5-OXO-4,5-DIHVDRO-L,2,4-OXADIAZOL-3-VL)BIPHENYI-4-VL]METHYL}- LH-BENZIMIDAZOLE-7-CARBOXYIATE AND ITS SALTS | MSN LABORATORIES LIMITED (IN) | 2013-12-19 | — | — | WO | claimed |
| US-9527850-B2 | Benzyl piperidine compounds as lysophosphatidic acid (LPA) receptor antagonist | MERCK PATENT GMBH (DE) | 2016-12-27 | — | — | US | disclosed |
| US-20150011774-A1 | PROCESS FOR THE PREPARATION OF AZILSARTAN MEDOXOMIL OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | RANBAXY LABORATORIES LIMITED (IN) | 2015-01-08 | — | — | US | disclosed |
| US-20150011557-A1 | Benzyl Piperidine Compounds as Lysophosphatidic Acid (LPA) Receptor Antagonist | MERCK PATENT GMBH (DE) | 2015-01-08 | — | — | US | disclosed |
| WO-2013186792-A2 | PROCESS FOR THE PREPARATION OF (5-METHYL-2-OXO-L,3-DIOXOI-4-VL)METHVL 2- ETHOXV-L-{[2'-(5-OXO-4,5-DIHVDRO-L,2,4-OXADIAZOL-3-VL)BIPHENYI-4-VL]METHYL}- LH-BENZIMIDAZOLE-7-CARBOXYIATE AND ITS SALTS | MSN LABORATORIES LIMITED (IN) | 2013-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011557-A1 | Benzyl Piperidine Compounds as Lysophosphatidic Acid (LPA) Receptor Antagonist | LPAR1, LPAR2, LPAR5 | AGTR1 227/4885ABCB11 1865/4885EGFR 579/4885 |
| US-20150011774-A1 | PROCESS FOR THE PREPARATION OF AZILSARTAN MEDOXOMIL OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | REN, AGTR2, CYP4A11 | AGTR1 4/4885ABCB11 1615/4885EGFR 2573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.