SCHEMBL13974183

SCHEMBL13974183

C/C=C(/C)c1c(C)ncc(N=O)c1N

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20687578 0.63
SCHEMBL20687576 0.60 PIK3CD (0.32)
SCHEMBL24367631 0.60 NOS3 (0.35)
SCHEMBL27866570 0.59 NOS3 (0.56) KDM4EKMT2A
SCHEMBL14108031 0.58 PIK3CB (0.41)
SCHEMBL27707438 0.57 KDM4E (0.46) KDM4EKMT2A
SCHEMBL13484765 0.57 CCR1 (0.37) KMT2A
SCHEMBL15177936 0.57 MAPT (0.36)
SCHEMBL23264711 0.57 CCNA2 (0.35)
SCHEMBL20681192 0.56 KDM4E (0.44) KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090005371-A1 Substituted Fused [1,2]Imidazo[4,5-C] Ring Compounds and Methods 3M INNOVATIVE PROPERTIES COMPANY 2009-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090005371-A1 Substituted Fused [1,2]Imidazo[4,5-C] Ring Compounds and Methods IL2, IFNG, IL4 KDM4E 3148/4885KMT2A 3895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.