Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Isophthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.66 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.66 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.66 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.66 |
| ▸ | ANPEP | P15144 | 2/20 | 0.58 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.51 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amphetamine SCHEMBL21464672 | 0.93 | TAAR1 (0.70) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| Amphetamine SCHEMBL29185448 | 0.93 | TAAR1 (0.70) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL1397444 | 0.91 | ANPEP (0.69) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL14478232 | 0.91 | ANPEP (0.69) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL9622159 | 0.91 | ANPEP (0.69) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL27656347 | 0.90 | ANPEP (0.67) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| Isophthalic Acid SCHEMBL28041607 | 0.89 | TAAR1 (0.50) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| Isophthalic Acid SCHEMBL27506613 | 0.86 | FOLH1 (0.51) | ANPEPENPEPFOLH1MEP1B | |
| Amphetamine SCHEMBL29102142 | 0.83 | TAAR1 (0.79) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| Amphetamine SCHEMBL157108 | 0.83 | TAAR1 (0.79) | SLC6A2TAAR1MAOASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105385660-A | Hybridoma cell strain, antibody excreted by hybridoma cell strain, preparation method and application | HANGZHOU CLONGENE BIOTECH CO LTD | 2016-03-09 | — | — | CN | disclosed |