Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | PGR | P06401 | 5/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397707 | 0.85 | GRIN2D (0.63) | ALDH1A1LMNAPGRGRIN2DGRIN3B | |
| SCHEMBL2708459 | 0.81 | ALDH1A1 (0.77) | ALDH1A1LMNAPGRGRIN2DGRIN3B | |
| SCHEMBL12402356 | 0.80 | GRIN2D (0.39) | ALDH1A1LMNAPGRGRIN2DGRIN3B | |
| SCHEMBL1397714 | 0.80 | GRIN2D (0.42) | ALDH1A1LMNAPGRGRIN2DGRIN3B | |
| SCHEMBL1397817 | 0.80 | NPC1 (0.61) | ALDH1A1LMNAPGRGRIN2DGRIN3B | |
| SCHEMBL1397805 | 0.77 | ALDH1A1 (0.40) | ALDH1A1LMNAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1397879 | 0.77 | PGR (0.36) | ALDH1A1LMNAPGRGRIN2DGRIN3B | |
| SCHEMBL8234225 | 0.76 | ALDH1A1 (0.52) | ALDH1A1LMNAPGRGRIN2DGRIN3B | |
| SCHEMBL1397739 | 0.76 | MEN1 (0.36) | ALDH1A1LMNAPGRGRIN2DGRIN3B | |
| SCHEMBL1397841 | 0.73 | GRIN2D (0.36) | ALDH1A1LMNAPGRGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004601-B1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS AND PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MATRIX LAB LTD (IN) | 2011-03-02 | — | — | EP | claimed |
| US-20100160302-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS AND PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MYLAN LABORATORIES LIMITED (IN) | 2010-06-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160302-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS AND PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DPP4, DPP3, DPP7 | ALDH1A1 2103/4885LMNA 1938/4885PGR 3802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.