SCHEMBL2708459

SCHEMBL2708459

Nc1ccc(C23CC4CC(C2)CC(c2ccc(N)cc2)(C4)C3)cc1

nearest known ligand 0.77

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.77
LMNA P02545 4/20 0.77
PGR P06401 6/20 0.75
GRIN2D O15399 1/20 0.55
GRIN3B O60391 1/20 0.55
GRIN1 Q05586 1/20 0.55
GRIN2A Q12879 1/20 0.55
GRIN2B Q13224 1/20 0.55
GRIN2C Q14957 1/20 0.55
GRIN3A Q8TCU5 1/20 0.55
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
RAD52 P43351 1/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
ESR1 P03372 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2710493 0.89 ALDH1A1 (0.64) ALDH1A1LMNAPGRGRIN2DGRIN3B
SCHEMBL399431 0.87 ALDH1A1 (1.00) ALDH1A1LMNAPGRGRIN2DGRIN3B
Hydrochloric Acid SCHEMBL1983434 0.85 LMNA (0.96) ALDH1A1LMNAPGRGRIN2DGRIN3B
SCHEMBL17347307 0.83 ALDH1A1 (0.60) ALDH1A1LMNAPGRGRIN2DGRIN3B
SCHEMBL1397724 0.81 ALDH1A1 (0.58) ALDH1A1LMNAPGRGRIN2DGRIN3B
SCHEMBL18841462 0.79 ALDH1A1 (0.56) ALDH1A1LMNAPGRGRIN2DGRIN3B
SCHEMBL5886235 0.79 ALDH1A1 (0.56) ALDH1A1LMNAPGRMEN1KMT2A
SCHEMBL649556 0.79 ESR1 (0.60) ALDH1A1LMNAPGRGRIN2DGRIN3B
SCHEMBL6934914 0.79 PGR (0.51) ALDH1A1LMNAPGRGRIN2DGRIN3B
SCHEMBL16364512 0.79 ESR1 (0.60) ALDH1A1LMNAPGRGRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119286207-B Toughened and modified PBT (polybutylene terephthalate) and processing method thereof 浙江长鸿生物材料有限公司 2025-05-09 CN claimed
CN-119798589-A Polymeric resin and preparation method thereof, optical lens and intelligent glasses 珠海莫界科技有限公司 2025-04-11 CN claimed
CN-119286207-A Toughened and modified PBT (polybutylene terephthalate) and processing method thereof 浙江长鸿生物材料有限公司 2025-01-10 CN claimed
CN-114685743-B Low-temperature epoxy resin curing agent and preparation method thereof 韦尔通(厦门)科技股份有限公司 2023-01-31 CN claimed
CN-114685743-A Low-temperature epoxy resin curing agent and preparation method thereof 韦尔通(厦门)科技股份有限公司 2022-07-01 CN claimed
CN-119286207-B Toughened and modified PBT (polybutylene terephthalate) and processing method thereof 浙江长鸿生物材料有限公司 2025-05-09 CN disclosed
CN-119798589-A Polymeric resin and preparation method thereof, optical lens and intelligent glasses 珠海莫界科技有限公司 2025-04-11 CN disclosed
CN-119754731-A High-strength soluble bridge plug 江苏威捷四通能源科技有限公司 2025-04-04 CN disclosed
CN-119485936-A Flame-retardant flexible circuit board and preparation method thereof 德兴市恒海科技有限公司 2025-02-18 CN disclosed
CN-119286207-A Toughened and modified PBT (polybutylene terephthalate) and processing method thereof 浙江长鸿生物材料有限公司 2025-01-10 CN disclosed
CN-114685743-B Low-temperature epoxy resin curing agent and preparation method thereof 韦尔通(厦门)科技股份有限公司 2023-01-31 CN disclosed
CN-114685743-A Low-temperature epoxy resin curing agent and preparation method thereof 韦尔通(厦门)科技股份有限公司 2022-07-01 CN disclosed
CN-107673977-A A kind of preparation method of the aromatic diamine containing adamantane structure 上海博栋化学科技有限公司 2018-02-09 CN disclosed
EP-2000510-B1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM SUMITOMO BAKELITE CO (JP) 2012-05-02 EP disclosed
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-20090118431-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE COMPANY, LTD (JP) 2009-05-07 US disclosed
EP-2000510-A1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM Sumitomo Bakelite Company, Ltd. (JP) 2008-12-10 EP disclosed
US-7365231-B2 Compound with antitumor activity and preparation method therefor NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2008-04-29 US disclosed
US-20060241187-A1 Compound with antitumor activity and preparation method therefor NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) 2006-10-26 US disclosed
US-6265753-B1 IMIDIZING AND CURING AN OLIGOMERIC PRECURSOR COMPOUND COMPRISING A POLYBENZOXAZOLE, POLYBEZOTHIAZOLE POLYAMIC ACID ESTER END-CAPPED WITH AN ARYL-SUBSTITUTED ACETYLENE MOIETY; ENHANCED ISOTROPIC OPTICAL AND DIELECTRICAL PROPERTIES INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241187-A1 Compound with antitumor activity and preparation method therefor WEE1, WEE2, CYP51A1 ALDH1A1 206/4885LMNA 2945/4885PGR 2516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.