Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15233084 | 0.81 | KDM2B (0.39) | PTPN1HPGDSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13525672 | 0.79 | KMT2A (0.50) | PTPN1HPGDSMN1; SMN2KDM4ECES2 | |
| SCHEMBL17311212 | 0.77 | CA12 (0.46) | KDM4EMAPTKMT2AMEN1TDP1 | |
| SCHEMBL30368172 | 0.77 | CA12 (0.46) | KDM4EMAPTKMT2AMEN1TDP1 | |
| SCHEMBL13655554 | 0.76 | HDAC1 (0.57) | HPGDNPC1RAB9AHDAC1HDAC8 | |
| SCHEMBL14765363 | 0.75 | PTPN1 (0.67) | PTPN1HPGDSMN1; SMN2KDM4ECES2 | |
| SCHEMBL4257933 | 0.75 | PTPN1 (0.67) | PTPN1HPGDSMN1; SMN2KDM4ECES2 | |
| SCHEMBL26922809 | 0.75 | KMO (0.47) | HPGDKDM4EALDH1A1HDAC1HDAC8 | |
| SCHEMBL29489791 | 0.75 | PTPN1 (0.71) | PTPN1HPGDSMN1; SMN2KDM4ECES2 | |
| SCHEMBL1974978 | 0.75 | PTPN1 (0.71) | PTPN1HPGDSMN1; SMN2KDM4ECES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9505799-B2 | 18F-labeled precursor of PET radioactive medical supplies, and preparation method thereof | FUTURECHEM CO., LTD. (KR) | 2016-11-29 | — | — | US | disclosed |
| US-9505799-B2 | 18F-labeled precursor of PET radioactive medical supplies, and preparation method thereof | FUTURECHEM CO., LTD. (KR) | 2016-11-29 | — | — | US | disclosed |
| US-20140194620-A1 | 18F-LABELED PRECURSOR OF PET RADIOACTIVE MEDICAL SUPPLIES, AND PREPARATION METHOD THEREOF | FUTURECHEM CO., LTD. (KR) | 2014-07-10 | — | — | US | disclosed |
| US-20140194620-A1 | 18F-LABELED PRECURSOR OF PET RADIOACTIVE MEDICAL SUPPLIES, AND PREPARATION METHOD THEREOF | FUTURECHEM CO., LTD. (KR) | 2014-07-10 | — | — | US | disclosed |
| WO-2012168733-A1 | SUBSTITUTED 8 - AMINO - IMIDAZO [1, 2-A] PYRAZINES AS ANTIBACTERIAL AGENTS | UCL BUSINESS PLC (GB) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012168733-A1 | SUBSTITUTED 8 - AMINO - IMIDAZO [1, 2-A] PYRAZINES AS ANTIBACTERIAL AGENTS | UCL BUSINESS PLC (GB) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012157900-A2 | 18F-LABELED PRECURSOR OF PET RADIOACTIVE MEDICAL SUPPLIES, AND PREPARATION METHOD THEREOF | 서강대학교산학협력단 (KR) | 2012-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140194620-A1 | 18F-LABELED PRECURSOR OF PET RADIOACTIVE MEDICAL SUPPLIES, AND PREPARATION METHOD THEREOF | SLC43A1, SLC7A5, SLC35B2 | PTPN1 4490/4885HPGD 3315/4885SMN1; SMN2 4030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.