Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13977937 | 0.76 | NPC1 (0.39) | KDM4EPOLBKMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL28676955 | 0.75 | F7 (0.57) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL13978226 | 0.75 | KMT2A (0.45) | F7F3POLBKMT2AMEN1 | |
| SCHEMBL312479 | 0.73 | F7 (0.59) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL29692126 | 0.73 | F7 (0.59) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL27764447 | 0.73 | F7 (0.59) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL283480 | 0.73 | F7 (0.59) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL834568 | 0.73 | F7 (0.59) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL283482 | 0.73 | F7 (0.59) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL24170739 | 0.72 | F7 (0.57) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012156920-A1 | BIO-ORTHOGONAL DRUG ACTIVATION | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-11-22 | — | — | WO | disclosed |