Sugi Predict

Sugi Predict / Compounds / SCHEMBL283480

SCHEMBL283480

SCHEMBL283480

N/C(=N/O)c1cccnc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F7 P08709 1/20 0.59
▸ F3 P13726 1/20 0.59
▸ SARM1 Q6SZW1 1/20 0.59
▸ SIRT2 Q8IXJ6 1/20 0.59
▸ SIRT6 Q8N6T7 1/20 0.59
▸ SIRT1 Q96EB6 1/20 0.59
▸ SIRT3 Q9NTG7 1/20 0.59
▸ SIRT5 Q9NXA8 1/20 0.59
▸ SIRT4 Q9Y6E7 1/20 0.59
▸ POLB P06746 2/20 0.52
▸ ALDH1A1 P00352 2/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ APP P05067 1/20 0.50
▸ GAA P10253 1/20 0.50
▸ HCAR3 P49019 1/20 0.50
▸ HCAR2 Q8TDS4 1/20 0.50
▸ MEN1 O00255 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ HTT P42858 1/20 0.49
▸ NPC1 O15118 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283482 1.00 F7 (0.59) F7F3SARM1SIRT2SIRT6
SCHEMBL312479 1.00 F7 (0.59) F7F3SARM1SIRT2SIRT6
SCHEMBL29692126 1.00 F7 (0.59) F7F3SARM1SIRT2SIRT6
Hydrochloric Acid SCHEMBL28676955 0.98 F7 (0.57) F7F3SARM1SIRT2SIRT6
Niacin SCHEMBL9231503 0.89 ALDH1A1 (0.70) F7F3SARM1SIRT2SIRT6
SCHEMBL834568 0.83 F7 (0.59) F7F3SARM1SIRT2SIRT6
SCHEMBL27764447 0.83 F7 (0.59) F7F3SARM1SIRT2SIRT6
SCHEMBL24170739 0.82 F7 (0.57) F7F3SARM1SIRT2SIRT6
SCHEMBL5056593 0.79 CYP3A4 (0.54) F7F3SARM1SIRT2SIRT6
SCHEMBL22281477 0.79 CYP3A4 (0.54) F7F3SARM1SIRT2SIRT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3885340-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2024-11-27 — — EP disclosed
CN-115304591-B Bridged ring steroid synthetase inhibitor and preparation method and application thereof 广州中医药大学(广州中医药研究院) 2024-10-01 — — CN disclosed
EP-3885340-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2021-09-29 — — EP disclosed
US-11046713-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2021-06-29 — — US disclosed
EP-3369732-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2021-05-26 — — EP disclosed
US-20200299307-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2020-09-24 — — US disclosed
US-10711013-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2020-07-14 — — US disclosed
US-20190100536-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2019-04-04 — — US disclosed
US-10118933-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2018-11-06 — — US disclosed
EP-3369732-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2018-09-05 — — EP disclosed
US-20130196967-A1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF LEUKOTRIENE PRODUCTION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-08-01 — — US disclosed
US-20130196967-A1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF LEUKOTRIENE PRODUCTION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-08-01 — — US disclosed
US-20120225867-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2012-09-06 — — US disclosed
US-8188135-B2 Compounds as cannabinoid receptor ligands ABBOTT LABORATORIES (US) 2012-05-29 — — US disclosed
EP-2428507-A2 Cannabinoid receptor ligands Abbott Laboratories (US) 2012-03-14 — — EP disclosed
EP-2334646-A2 SUBSTITUTED BENZAMIDES AS CANNABINOID RECEPTOR LIGANDS Abbott Laboratories (US) 2011-06-22 — — EP disclosed
WO-2010033543-A2 NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2010-03-25 — — WO disclosed
US-20100069348-A1 NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2010-03-18 — — US disclosed
US-20100069349-A1 NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2010-03-18 — — US disclosed
EP-0641797-A1 Cephem derivatives and antimicrobial agents containing the same KATAYAMA SEIYAKUSYO CO. Ltd. (JP) 1995-03-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10118933-B2 Androgen receptor modulating compounds AR, NR5A1, SHBG F7 4366/4885F3 4208/4885SARM1 985/4885
US-20100069348-A1 NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS CNR1, CNR2, NPY1R F7 1435/4885F3 2975/4885SARM1 1905/4885
US-20130196967-A1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF LEUKOTRIENE PRODUCTION LTB4R, LTC4S, LTB4R2 F7 226/4885F3 123/4885SARM1 1014/4885
US-20100069349-A1 NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS CNR1, CNR2, NPY1R F7 1435/4885F3 2975/4885SARM1 1905/4885
US-10711013-B2 Androgen receptor modulating compounds AR, NR5A1, SHBG F7 4366/4885F3 4208/4885SARM1 985/4885
US-20200299307-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG F7 4366/4885F3 4208/4885SARM1 985/4885
US-20190100536-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG F7 4366/4885F3 4208/4885SARM1 985/4885
US-11046713-B2 Androgen receptor modulating compounds AR, NR5A1, SHBG F7 4366/4885F3 4208/4885SARM1 985/4885
US-20120225867-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG F7 4366/4885F3 4208/4885SARM1 985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.