Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | SI | P14410 | 4/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | BRD1 | O95696 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238811 | 0.85 | MAPT (0.45) | NPC1MAPTRAB9ACOXFA4PKM | |
| SCHEMBL13877343 | 0.83 | MAPT (0.43) | NPC1MAPTRAB9ACOXFA4PKM | |
| SCHEMBL18101747 | 0.82 | AKT1 (0.40) | NPC1MAPTRAB9ACOXFA4PKM | |
| SCHEMBL18101763 | 0.82 | AKT1 (0.40) | NPC1MAPTRAB9ACOXFA4PKM | |
| Hydrochloric Acid SCHEMBL27777901 | 0.81 | MAPT (0.42) | NPC1MAPTRAB9ACOXFA4PKM | |
| Hydrochloric Acid SCHEMBL4372394 | 0.81 | MAPT (0.42) | NPC1MAPTRAB9ACOXFA4PKM | |
| SCHEMBL30513267 | 0.78 | AKT1 (0.56) | NPC1MAPTRAB9ACOXFA4PKM | |
| SCHEMBL3184205 | 0.78 | AKT1 (0.56) | NPC1MAPTRAB9ACOXFA4PKM | |
| SCHEMBL12465725 | 0.78 | PKM (0.41) | NPC1MAPTRAB9ACOXFA4PKM | |
| SCHEMBL5037678 | 0.78 | COXFA4 (0.42) | NPC1MAPTRAB9ACOXFA4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558235-B1 | METHODS OF TREATMENT DURING VASCULAR PROCEDURES | ALLERGAN INC (US) | 2008-12-10 | — | — | EP | disclosed |