Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12907530 | 0.96 | NPC1 (0.40) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| Trifluoromethanesulfonic Acid SCHEMBL4800357 | 0.92 | L3MBTL1 (0.37) | L3MBTL1MAOBCASP3SENP8SENP7 | |
| SCHEMBL7532893 | 0.87 | DHODH (0.36) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL4802002 | 0.87 | PLA2G2A (0.48) | L3MBTL1MAOBPLA2G2ALMNAHPGD | |
| SCHEMBL4189457 | 0.85 | LCK (0.39) | MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13633576 | 0.85 | LCK (0.39) | MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4187176 | 0.84 | MCL1 (0.39) | L3MBTL1MAOBLMNANPC1ATM | |
| SCHEMBL13979973 | 0.83 | TDP1 (0.35) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL13979971 | 0.83 | LMNA (0.43) | L3MBTL1LMNAHPGDNPC1PKM | |
| SCHEMBL7538206 | 0.83 | NPC1 (0.37) | L3MBTL1CASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459284-B2 | Chemiluminescent acridinium compounds and analogues thereof as substrates of hydrolytic enzymes | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2008-12-02 | — | — | US | disclosed |