Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CBS | P35520 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933862 | 0.73 | CSNK2A2 (0.57) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL14066713 | 0.69 | CBS (0.74) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL7369647 | 0.69 | TERT (0.74) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL13980461 | 0.67 | NPC1 (0.55) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3925359 | 0.66 | ESR1 (0.68) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL13233406 | 0.65 | TERT (0.49) | ESR1ESR2TERT | |
| SCHEMBL1119325 | 0.65 | ESR1 (1.00) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL30482423 | 0.64 | ESR1 (0.56) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3936717 | 0.64 | ESR1 (1.00) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3927649 | 0.64 | ESR1 (1.00) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458700-B1 | SUBSTITUTED 2-PHENYL BENZOFURANS AS ESTROGENIC AGENTS | WYETH CORP (US) | 2008-12-03 | — | — | EP | disclosed |