Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 4/20 | 0.74 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.62 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.62 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649959 | 0.85 | TERT (1.00) | TERTCSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL31322174 | 0.85 | TERT (1.00) | TERTCSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL7378162 | 0.85 | CYP3A4 (0.76) | TERTCSNK2A2CSNK2BCSNK2A1CYP1A1 | |
| SCHEMBL30269738 | 0.83 | CYP1A2 (0.67) | TERTCSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL7377070 | 0.82 | CSNK2A2 (0.86) | TERTCSNK2A2CSNK2BCSNK2A1KDM4E | |
| SCHEMBL7371867 | 0.81 | TERT (0.64) | TERTCSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL7375040 | 0.80 | TERT (0.65) | TERTCSNK2A2CSNK2BCSNK2A1TDP1 | |
| SCHEMBL14066713 | 0.79 | CBS (0.74) | CSNK2A2CSNK2BCSNK2A1TDP1CYP1A1 | |
| SCHEMBL7377517 | 0.79 | CSNK2A2 (0.67) | TERTCSNK2A2CSNK2BCSNK2A1BRD4 | |
| SCHEMBL311865 | 0.79 | TERT (0.68) | TERTCSNK2A2CSNK2BCSNK2A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115718-A1 | HYDROXYFLAVONE DERIVATIVES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017184-A1 | HYDROXYFLAVONE DERIVATIVES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-03-30 | — | — | WO | disclosed |