Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | THRB | P10828 | 3/20 | 0.74 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.67 |
| ▸ | APP | P05067 | 4/20 | 0.67 |
| ▸ | PARP1 | P09874 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.66 |
| ▸ | SLCO2B1 | O94956 | 4/20 | 0.66 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.66 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.66 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.66 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.66 |
| ▸ | PKM | P14618 | 4/20 | 0.66 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.66 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sumaflavone SCHEMBL30152146 | 1.00 | KMT2A (0.74) | KMT2ATDP1MEN1THRBPTPN1 | |
| Amentoflavone SCHEMBL29929632 | 0.89 | MEN1 (0.80) | KMT2ATDP1MEN1THRBPTPN1 | |
| Amentoflavone SCHEMBL29497539 | 0.89 | MEN1 (0.80) | KMT2ATDP1MEN1THRBPTPN1 | |
| Amentoflavone SCHEMBL312563 | 0.89 | MEN1 (0.80) | KMT2ATDP1MEN1THRBPTPN1 | |
| Amentoflavone SCHEMBL4649212 | 0.88 | MEN1 (0.79) | KMT2ATDP1MEN1THRBPTPN1 | |
| Robustaflavone SCHEMBL561807 | 0.86 | APP (0.77) | KMT2ATDP1MEN1THRBPTPN1 | |
| Robustaflavone SCHEMBL7643511 | 0.85 | APP (0.76) | KMT2ATDP1MEN1THRBPTPN1 | |
| Robustaflavone SCHEMBL7638211 | 0.85 | APP (0.76) | KMT2ATDP1MEN1THRBPTPN1 | |
| Sotetsuflavone SCHEMBL4467051 | 0.84 | APP (0.80) | KMT2ATDP1MEN1THRBPTPN1 | |
| Sotetsuflavone SCHEMBL30646165 | 0.84 | APP (0.80) | KMT2ATDP1MEN1THRBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147022-A1 | ANTI-WRINKLE COMPOSITION FOR EXTERNAL APPLICATIONS TO THE SKIN CONTAINING BIFLAVONOID DERIVATIVES | AMOREPACIFIC CORPORATION (KR) | 2008-12-04 | — | — | WO | disclosed |