Robustaflavone

Robustaflavone

SCHEMBL561807

O=c1cc(-c2ccc(O)c(-c3c(O)cc4oc(-c5ccc(O)cc5)cc(=O)c4c3O)c2)oc2cc(O)cc(O)c12

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.77
MMP3 P08254 2/20 0.77
MMP9 P14780 2/20 0.77
KMT2A Q03164 7/20 0.72
MEN1 O00255 6/20 0.72
THRB P10828 3/20 0.72
TDP1 Q9NUW8 3/20 0.72
PTPN1 P18031 2/20 0.71
CYP1A1 P04798 5/20 0.70
CYP1B1 Q16678 5/20 0.70
FTO Q9C0B1 5/20 0.70
ABCB1 P08183 5/20 0.70
POLH Q9Y253 5/20 0.70
ALDH1A1 P00352 5/20 0.70
MAPT P10636 5/20 0.70
SLCO2B1 O94956 4/20 0.70
CYP1A2 P05177 4/20 0.70
KDM4E B2RXH2 4/20 0.70
CYP3A4 P08684 4/20 0.70
HPGD P15428 4/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Robustaflavone SCHEMBL7638211 0.99 APP (0.76) APPMMP3MMP9KMT2AMEN1
Robustaflavone SCHEMBL7643511 0.99 APP (0.76) APPMMP3MMP9KMT2AMEN1
Robustaflavone SCHEMBL624405 0.94 APP (0.69) APPMMP3MMP9KMT2AMEN1
SCHEMBL17166016 0.92 APP (0.70) APPMMP3MMP9KMT2AMEN1
Robustaflavone SCHEMBL7454193 0.90 KMT2A (0.66) APPMMP3MMP9KMT2AMEN1
Robustaflavone SCHEMBL7517639 0.89 APP (0.67) APPMMP3MMP9KMT2AMEN1
Amentoflavone SCHEMBL312563 0.88 MEN1 (0.80) APPMMP3MMP9KMT2AMEN1
Amentoflavone SCHEMBL29497539 0.88 MEN1 (0.80) APPMMP3MMP9KMT2AMEN1
Amentoflavone SCHEMBL29929632 0.88 MEN1 (0.80) APPMMP3MMP9KMT2AMEN1
SCHEMBL17166286 0.87 APP (1.00) APPMMP3MMP9KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 408 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025024478-A1 COMPOSITIONS FOR THE MODULATION OF TASTE IXORA SCIENTIFIC INC. (US) 2025-01-30 WO claimed
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 WO claimed
CN-115785113-A Method for preparing Luwang bilobalide from Zanthoxylum avicennae and application of Luwang bilobalide 扬州大学 2023-03-14 CN claimed
CN-112516899-A Amide herbicide, blending equipment and blending method thereof 江苏云帆化工有限公司 2021-03-19 CN claimed
CN-111417309-A Herbicidal combination UPL有限公司 2020-07-14 CN claimed
CN-111417308-A Herbicidal combination UPL有限公司 2020-07-14 CN claimed
CN-111389052-A Preparation and application of polyamide high performance liquid chromatography column 中谱科技(福州)有限公司 2020-07-10 CN claimed
CN-106539958-A The pharmaceutical composition for the treatment of prolapse of lumbar intervertebral disc 济南昊雨青田医药技术有限公司 2017-03-29 CN claimed
CN-105663216-A Drug combination for treating coronary heart disease angina and preparation method thereof 济南星懿医药技术有限公司 2016-06-15 CN claimed
CN-105287693-A Pharmaceutical composition for treating vitiligo and preparation method thereof JINAN XINGYI MED TECH CO LTD 2016-02-03 CN claimed
US-6225481-B1 REACTING 6-IODO-5,7,4'-TRIMETHOXYFLAVONE AND 5,7-4'-TRIMETHOXY-3'-(TRIMETHYLSTANNYL)FLAVONE IN PRESENCE OF PALLADIUM COMPOUND AND BASE TO PRODUCE ROBUSTAFLAVONE HEXAMETHYL ETHER, DEMETHYLATING TO PRODUCE ROBUSTAFLAVONE ADVANCED LIFE SCIENCES, INC. 2001-05-01 US claimed
CN-1274354-A Robustaflavone, intermediates and analogues and method for prepn. method MEDICHEM RES INC (US) 2000-11-22 CN claimed
EP-1007528-A2 ROBUSTAFLAVONE, INTERMEDIATES AND ANALOGUES AND METHOD FOR PREPARATION THEREOF MEDICHEM RESEARCH, INC. (US) 2000-06-14 EP claimed
WO-2000021514-A2 METHOD AND COMPOSITION FOR TREATING AND PREVENTING TUBERCULOSIS SARAWAK MEDICHEM PHARMACEUTICALS, INC. (US) 2000-04-20 WO claimed
US-5948918-A PLANT EXTRACTS MEDICHEM RESEARCH, INC. (US) 1999-09-07 US claimed
WO-1999010292-A2 ROBUSTAFLAVONE, INTERMEDIATES AND ANALOGUES AND METHOD FOR PREPARATION THEREOF MEDICHEM RESEARCH, INC. (US) 1999-03-04 WO claimed
WO-1998046238-A1 BIFLAVINOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS, ALONE OR IN COMBINATION WITH AT LEAST ONE KNOWN ANTIVIRAL AGENT MEDICHEM RESEARCH, INC. (US) 1998-10-22 WO claimed
US-5773462-A INFLUENZA THERAPY MEDICHEM RESEARCH, INC. (US) 1998-06-30 US claimed
EP-0833631-A1 BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS MEDICHEM RESEARCH, INC. (US) 1998-04-08 EP claimed
WO-1997000679-A1 BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS MEDICHEM RESEARCH, INC. (US) 1997-01-09 WO claimed