Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | KHK | P50053 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | S100B | P04271 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3540996 | 0.85 | MAPT (0.56) | MAPTKDM4EALDH1A1PKMGAA | |
| SCHEMBL22171241 | 0.82 | GAA (0.62) | MAPTKDM4EALDH1A1PKMGAA | |
| SCHEMBL3531372 | 0.81 | GAA (0.67) | MAPTKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL22171249 | 0.81 | MAPT (0.51) | MAPTKDM4EALDH1A1PKMGAA | |
| Hydrochloric Acid SCHEMBL22165259 | 0.79 | MAPT (0.50) | MAPTKDM4EALDH1A1PKMGAA | |
| SCHEMBL2550018 | 0.79 | GAA (0.61) | MAPTKDM4EALDH1A1PKMGAA | |
| SCHEMBL31208319 | 0.79 | GAA (0.61) | MAPTKDM4EALDH1A1PKMGAA | |
| SCHEMBL2205823 | 0.78 | MAPT (0.49) | MAPTKDM4EALDH1A1PKMGAA | |
| SCHEMBL2209498 | 0.78 | ALDH1A1 (0.49) | MAPTKDM4EALDH1A1PKMGAA | |
| SCHEMBL310368 | 0.78 | ALDH1A1 (0.49) | MAPTKDM4EALDH1A1PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162454-B1 | IMIDAZOPYRIDINE KINASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-01-02 | — | — | EP | disclosed |
| WO-2008150799-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-11 | — | — | WO | disclosed |