Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | S100B | P04271 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2550018 | 1.00 | GAA (0.61) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL19914428 | 0.98 | MAPT (0.65) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL31473820 | 0.83 | LGMN (0.67) | MAPTMEN1KMT2AALOX15HTT | |
| SCHEMBL3531372 | 0.83 | GAA (0.67) | GAAMAPTMEN1KMT2AHTT | |
| SCHEMBL4988458 | 0.83 | LGMN (0.67) | MAPTMEN1KMT2AALOX15HTT | |
| SCHEMBL19381718 | 0.82 | S100B (0.65) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL10290706 | 0.82 | L3MBTL1 (0.60) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL7296560 | 0.81 | TERT (0.48) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL7372826 | 0.81 | MAPT (0.68) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL31361984 | 0.81 | MAPT (0.68) | GAAMAPTMEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874074-B | HMOX1 inducers | 米托布里奇公司 | 2024-11-01 | — | — | CN | disclosed |