Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | S100B | P04271 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31208319 | 1.00 | GAA (0.61) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL19914428 | 0.98 | MAPT (0.65) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL31473820 | 0.83 | LGMN (0.67) | MAPTMEN1KMT2AALOX15HTT | |
| SCHEMBL3531372 | 0.83 | GAA (0.67) | GAAMAPTMEN1KMT2AHTT | |
| SCHEMBL4988458 | 0.83 | LGMN (0.67) | MAPTMEN1KMT2AALOX15HTT | |
| SCHEMBL19381718 | 0.82 | S100B (0.65) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL10290706 | 0.82 | L3MBTL1 (0.60) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL7296560 | 0.81 | TERT (0.48) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL7372826 | 0.81 | MAPT (0.68) | GAAMAPTMEN1KMT2AALOX15 | |
| SCHEMBL31361984 | 0.81 | MAPT (0.68) | GAAMAPTMEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240409533-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2024-12-12 | — | — | US | disclosed |
| US-12071433-B2 | HMOX1 inducers | Astellas Engineered Small Molecules US, Incorporated (US) | 2024-08-27 | — | — | US | disclosed |
| US-20240051952-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2024-02-15 | — | — | US | disclosed |
| US-20220177460-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2022-06-09 | — | — | US | disclosed |
| US-20220177460-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2022-06-09 | — | — | US | disclosed |
| EP-3952990-A1 | HMOX1 INDUCERS | Mitobridge, Inc. (US) | 2022-02-16 | — | — | EP | disclosed |
| CN-113874074-A | HMOX1 inducers | 米托布里奇公司 | 2021-12-31 | — | — | CN | disclosed |
| WO-2020210339-A1 | HMOX1 INDUCERS | MITOBRIDGE, INC. (US) | 2020-10-15 | — | — | WO | disclosed |
| US-10766888-B1 | HMOX1 inducers | MITOBRIDGE INC. (US) | 2020-09-08 | — | — | US | disclosed |
| US-10766888-B1 | HMOX1 inducers | MITOBRIDGE INC. (US) | 2020-09-08 | — | — | US | disclosed |
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2019-06-27 | — | — | US | disclosed |
| WO-2018037223-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2018-03-01 | — | — | WO | disclosed |
| WO-2015139883-A1 | COMPOSITION FOR ALTERING THE COLOR OF KERATIN FIBERS | L'OREAL (FR) | 2015-09-24 | — | — | WO | disclosed |
| EP-2552596-A2 | AIRBRUSH | L'Oréal (FR) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011121551-A2 | AN AIRBRUSH | L'OREAL (FR) | 2011-10-06 | — | — | WO | disclosed |
| WO-2010133640-A2 | DYEING COMPOSITION COMPRISING A SECONDARY PARA-PHENYLENEDIAMINE OXIDATION BASE AND A HETEROCYCLIC OXIDATION BASE | L'OREAL (FR) | 2010-11-25 | — | — | WO | disclosed |
| US-20080269191-A1 | Compounds for Nonsense Suppression, Use of These Compounds for the Manufacture of a Medicament for Treating Somatic Mutation-Related Diseases | PTC THERAPEUTICS, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| WO-2008037778-A2 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A DIAMINO-N, N-DIHYDROPYRAZOLONE DERIVATIVE AND A STABILIZER | L'OREAL (FR) | 2008-04-03 | — | — | WO | disclosed |
| EP-1812071-A2 | COMPOUNDS FOR NONSENSE SUPPRESSION, USE OF THESE COMPOUNDS FOR THE MANUFACTURE OF A MEDICAMENT FOR TREATING SOMATIC MUTATION-RELATED DISEASES | PTC Therapeutics, Inc. (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006044503-A2 | COMPOUNDS FOR NONSENSE SUPPRESSION, USE OF THESE COMPOUNDS FOR THE MANUFACTURE OF A MEDICAMENT FOR TREATING SOMATIC MUTATION-RELATED DISEASES | PTC THERAPEUTICS, INC. (US) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269191-A1 | Compounds for Nonsense Suppression, Use of These Compounds for the Manufacture of a Medicament for Treating Somatic Mutation-Related Diseases | UPF1, NSUN2, RNMT | GAA 184/4885MAPT 2955/4885MEN1 2168/4885 |
| US-10766888-B1 | HMOX1 inducers | HMOX1, HMOX2, HMBS | GAA 2202/4885MAPT 3846/4885MEN1 2693/4885 |
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | B3GNT2, RPN2, RPN1 | GAA 77/4885MAPT 1807/4885MEN1 725/4885 |
| US-20240409533-A1 | HMOX1 INDUCERS | HMOX1, HMOX2, HMBS | GAA 2202/4885MAPT 3846/4885MEN1 2693/4885 |
| US-12071433-B2 | HMOX1 inducers | HMOX1, HMOX2, HMBS | GAA 2123/4885MAPT 3756/4885MEN1 2434/4885 |
| US-20240051952-A1 | HMOX1 INDUCERS | HMOX1, HMOX2, QSOX1 | GAA 1965/4885MAPT 3238/4885MEN1 2900/4885 |
| US-20220177460-A1 | HMOX1 INDUCERS | HMOX1, HMOX2, HMBS | GAA 2123/4885MAPT 3756/4885MEN1 2434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.