SCHEMBL1398236

SCHEMBL1398236

C=CC(=O)NC(=N)N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL27709911 0.80 ALDH1A1 (0.50)
Biguanide SCHEMBL28649727 0.79 LMNA (0.53)
SCHEMBL8607631 0.78 TSHR (0.43)
Acrylamide SCHEMBL4630275 0.78 TSHR (0.65)
SCHEMBL1398274 0.78
SCHEMBL4297899 0.77
SCHEMBL7165464 0.76
SCHEMBL26217 0.76
SCHEMBL9322657 0.76
SCHEMBL7534808 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112236169-A Bifunctional small molecules targeting selective degradation of circulating proteins 耶鲁大学 2021-01-15 CN claimed
EP-2764065-B1 SACRIFICIAL ADHESIVE COATINGS ROCHAL IND LLC (US) 2017-03-22 EP claimed
EP-2764065-A1 SACRIFICIAL ADHESIVE COATINGS Rochal Industries, LLP (US) 2014-08-13 EP claimed
WO-2013052276-A1 SACRIFICIAL ADHESIVE COATINGS ROCHAL INDUSTRIES, LLP (US) 2013-04-11 WO claimed
US-8263720-B1 Sacrificial adhesive coatings ROCHAL INDUSTRIES, LLP (US) 2012-09-11 US claimed
CN-1196721-A Heteroaryl-substituted acryloylguanidine derivatives and medicinal composition thereof YAMANOUCHI PHARMA CO LTD (JP) 1998-10-21 CN claimed
EP-0861831-A1 HETEROARYL-SUBSTITUTED ACRYLOYLGUANIDINE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1998-09-02 EP claimed
JP-9059245-A None JP disclosed
CN-115667388-B Resin composition and molded article 三菱化学株式会社 2025-05-30 CN disclosed
CN-119789954-A Laminate and method for producing same 三菱化学株式会社 2025-04-08 CN disclosed
US-11839626-B2 Composition and kits for inhibition of pathogenic microbial infection and methods of using the same ROCHAL TECHNOLOGIES LLC (US) 2023-12-12 US disclosed
WO-2021242052-A1 ANTIBACTERIAL POLYMER COMPOSITION 주식회사 엘지화학 2021-12-02 WO disclosed
WO-2021096230-A1 SUPERABSORBENT POLYMER AND PREPARATION METHOD THEREFOR 주식회사 엘지화학 2021-05-20 WO disclosed
CN-1196721-A Heteroaryl-substituted acryloylguanidine derivatives and medicinal composition thereof YAMANOUCHI PHARMA CO LTD (JP) 1998-10-21 CN disclosed
EP-0861831-A1 HETEROARYL-SUBSTITUTED ACRYLOYLGUANIDINE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1998-09-02 EP disclosed
EP-0861831-A1 HETEROARYL-SUBSTITUTED ACRYLOYLGUANIDINE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1998-09-02 EP disclosed
EP-0855392-A2 Five-membered heterocycles having biphenylsulphonyl substituents, processes for the preparation thereof, their use as medicaments or diagnostic agent and medicaments containing them HOECHST AKTIENGESELLSCHAFT (DE) 1998-07-29 EP disclosed
WO-1997011055-A1 HETEROARYL-SUBSTITUTED ACRYLOYLGUANIDINE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1997-03-27 WO disclosed
JP-H0959245-A N-(2-PROPENOYL)GUANIDINE DERIVATIVE YAMANOUCHI PHARMACEUT CO LTD 1997-03-04 JP disclosed
US-4229443-A Derivatives of penicillanic acid LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) 1980-10-21 US disclosed