⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5470839 | 0.81 | — | — | |
| SCHEMBL25369963 | 0.81 | TSHR (0.53) | — | |
| SCHEMBL14520341 | 0.79 | ALDH1A1 (0.31) | — | |
| SCHEMBL1398236 | 0.77 | — | — | |
| SCHEMBL38662571 | 0.75 | — | — | |
| Bicarbonate SCHEMBL30774952 | 0.72 | ACHE (0.40) | — | |
| SCHEMBL2767461 | 0.72 | — | — | |
| Bicarbonate SCHEMBL19458454 | 0.72 | ACHE (0.40) | — | |
| SCHEMBL1169064 | 0.71 | — | — | |
| SCHEMBL909232 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119463012-A | PH responsive hydrogel and preparation method and application thereof | 中山大学 | 2025-02-18 | — | — | CN | disclosed |
| US-20090269406-A1 | Therapeutic uses of biocompatible biogel compositions | PANITCH ALYSSA | 2009-10-29 | — | — | US | disclosed |
| CN-1249026-C | N-guanidinoalkylamides, their preparation, their use, and pharmaceutical preparations containing them | AVENTIS PHARMA GMBH (DE) | 2006-04-05 | — | — | CN | disclosed |
| US-6664393-B2 | Anticoagulants | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-12-16 | — | — | US | disclosed |
| US-20030162967-A1 | Novel N-guanidinoalkylamides, their preparation, their use, and pharmaceutical preparations comprising them | AVENTIS PHARMA DEUTSCHLAND GMBH | 2003-08-28 | — | — | US | disclosed |
| CN-1387508-A | N-guanidinoalkylamides, their preparation, their use, and pharmaceutical preparations comprising them | AVENTIS PHARMA GMBH (DE) | 2002-12-25 | — | — | CN | disclosed |
| US-6472562-B1 | SUCH AS 4-NITRO-N-(1-CARBAMOYL-4-GUANIDINOBUTYL)-3-(2-(2,4 -DICHLOROPHENYL)ETHOXY)BENZAMIDE; ANTITHROMBOTICS; CARDIOVAS-CULAR DISORDERS LIKE THROMBOEMBOLICS OR RESTENOSES; REVERSI-BLE INHIBITORS OF BLOOD CLOTTING ENZYMES FACTOR XA, VIIA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-10-29 | — | — | US | disclosed |
| EP-1095933-A1 | Novel N-guanidinoalkylamides, their preparation, their use, and pharmaceutical preparations comprising them | Aventis Pharma Deutschland GmbH (DE) | 2001-05-02 | — | — | EP | disclosed |
| US-5252574-A | Hypotensive agents, vision disorder | MERCK & CO., INC. (US) | 1993-10-12 | — | — | US | disclosed |