SCHEMBL1398261

SCHEMBL1398261

Nc1cccc2c1C(O)OC2=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.37
PTPRC P08575 1/20 0.37
ALDH1A1 P00352 3/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
F2 P00734 1/20 0.33
PARP1 P09874 2/20 0.33
PABPC1 P11940 2/20 0.33
HSPA1A P0DMV8 1/20 0.33
CSNK1A1 P48729 2/20 0.32
CSNK1D P48730 2/20 0.32
CSNK1G1 Q9HCP0 2/20 0.32
AURKA O14965 1/20 0.32
AURKB Q96GD4 1/20 0.32
INCENP Q9NQS7 1/20 0.32
FGR P09769 1/20 0.32
PIM1 P11309 1/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19807346 0.78 MAOA (0.42) ALDH1A1KDM4EMEN1KMT2APARP1
SCHEMBL3890561 0.77 SMARCA2 (0.36) ALDH1A1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL3744088 0.77 CA1 (0.42) MEN1KMT2AMAOAPDK2POLB
SCHEMBL3902371 0.77 MAP3K14 (0.40) ALDH1A1MEN1KMT2APOLB
SCHEMBL14911427 0.77 CA1 (0.38) ALDH1A1MEN1KMT2APARP1CSNK1A1
SCHEMBL5423222 0.77 SMN1; SMN2 (0.32) ALDH1A1MEN1KMT2ASMN1; SMN2POLB
SCHEMBL3901331 0.73 AR (0.44) PTPRCALDH1A1L3MBTL1KDM4EMEN1
SCHEMBL20552496 0.73 AR (0.44) PTPRCALDH1A1L3MBTL1KDM4EMEN1
SCHEMBL16513031 0.72 ALDH1A1 (0.41) PTPRCALDH1A1MEN1KMT2APARP1
SCHEMBL21421359 0.72 ALOX15 (0.38) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4570901-A1 METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS Buddhist Tzu Chi Medical Foundation (TW) 2025-06-18 EP claimed
CN-120137900-A Method for selectively removing undifferentiated pluripotent stem cells 佛教慈济医疗财团法人 2025-06-13 CN claimed
US-20250188411-A1 METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS BUDDHIST TZU CHI MEDICAL FOUNDATION (TW) 2025-06-12 US claimed
EP-0476474-B1 4-Amino-3-hydroxy-phthalide and a method for its preparation BAYER AG (DE) 1994-12-28 EP claimed
EP-0627427-A1 3-Quinolyl substituted dihydropyridines, process for their preparation and their use in drugs BAYER AG (DE) 1994-12-07 EP claimed
EP-0593930-A1 3-Substituted quinoline-5-carboxylic acids BAYER AG (DE) 1994-04-27 EP claimed
US-5270469-A Process of preparing 3-phenyl-quinoline-5-carboxylic acid BAYER AKTIENGESELLSCHAFT (DE) 1993-12-14 US claimed
US-5210231-A 4-AMINO-3-HYDROXY-PHTHALIDE, AND A PROCESS FOR ITS PREPARATION BAYER AKTIENGESELLSCHAFT (DE) 1993-05-11 US claimed
EP-0476474-A1 4-Amino-3-hydroxy-phthalide and a method for its preparation BAYER AG (DE) 1992-03-25 EP claimed
JP-6211796-A None JP disclosed
JP-4368377-A None JP disclosed
EP-4570901-A1 METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS Buddhist Tzu Chi Medical Foundation (TW) 2025-06-18 EP disclosed
CN-120137900-A Method for selectively removing undifferentiated pluripotent stem cells 佛教慈济医疗财团法人 2025-06-13 CN disclosed
US-20250188411-A1 METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS BUDDHIST TZU CHI MEDICAL FOUNDATION (TW) 2025-06-12 US disclosed
EP-0515940-A1 New 2-amino-5-cyano-1,4-dihydropyridines, process for their preparation and use in pharmaceutical compositions BAYER AG (DE) 1992-12-02 EP disclosed
US-5100900-A Inotropic agents BAYER AKTIENGESELLSCHAFT (DE) 1992-03-31 US disclosed
EP-0476474-A1 4-Amino-3-hydroxy-phthalide and a method for its preparation BAYER AG (DE) 1992-03-25 EP disclosed
EP-0476474-A1 4-Amino-3-hydroxy-phthalide and a method for its preparation BAYER AG (DE) 1992-03-25 EP disclosed
EP-0476474-A1 4-Amino-3-hydroxy-phthalide and a method for its preparation BAYER AG (DE) 1992-03-25 EP disclosed
EP-0452712-A1 4-Quinolyl-dihydropyridines, process for their prepatation and their use in medicaments BAYER AG (DE) 1991-10-23 EP disclosed